New stomach muscle cut aims to curb appetite and shed pounds
NCT ID NCT05711758
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This pilot study tests a new procedure called PSAM (Pylorus-Sparing Antral Myotomy) for weight loss in 30 adults with obesity. The procedure involves cutting some stomach muscles to slow down how fast food leaves the stomach, which may help people feel full longer and lose weight. Researchers are checking if it is safe, tolerable, and effective on its own, without combining it with other weight-loss procedures.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Pylorus-Sparing Antral Myotomy (PSAM) procedure
What this could lead to
If successful, PSAM could offer a new, less invasive weight-loss option for people with obesity, potentially reducing procedure time and risks compared to current methods.
What could go wrong
This is a very small pilot study with only 30 people, so results may not apply to everyone. The procedure is new and its long-term safety and effectiveness are unknown.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Brigham and Women's Hospital
RECRUITINGBoston, Massachusetts, 02115, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••