New gel combo for aching muscles: does it beat standard pain relievers?

NCT ID NCT07475663

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether a gel containing piroxicam plus warming and cooling ingredients (methyl salicylate, menthol, eugenol) works as well as standard piroxicam-only or diclofenac gels for muscle and joint pain. 180 adults with conditions like ankle sprain, back pain, or knee osteoarthritis used one of the three gels for about 6 days. Researchers measured pain reduction using a standard pain questionnaire.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Piroxicam plus counterirritant gel (Methyl Salicylate, Menthol, Eugenol)

What this could lead to

If it works, this could offer a similar pain relief option with added cooling and warming sensations for muscle and joint pain.

What could go wrong

This is a completed Phase 3 trial, but results may not apply to all types of pain or long-term use. The study is relatively small (180 people) and short (6 days).

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

ankle injury Back Pain epicondylitis osteoarthritis osteoarthritis, knee patellofemoral pain syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • St. Carolus Sports Clinic & Klinik Utama Eminence

    Jakarta, DKI Jakarta, 10440, Indonesia