Knee surgery showdown: partial vs. total replacement for arthritis

NCT ID NCT01326156

Ongoing Disease control Sponsor: University of Aarhus Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two types of knee replacement surgery for people with arthritis limited to the kneecap area. One hundred patients will be randomly assigned to receive either a partial replacement (patellofemoral arthroplasty) or a full knee replacement. The goal is to see which surgery leads to better knee function, quality of life, and implant longevity over 10 years.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Knee replacement surgery (patellofemoral arthroplasty or total knee replacement)
What this could lead to: If successful, this could show that a smaller surgery (PFA) works as well as a full knee replacement for certain patients, leading to faster recovery and less bone removal.
What could go wrong: This is a relatively small trial (100 people) and results may not apply to everyone. Both surgeries carry standard risks like infection, blood clots, or implant failure over time.

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Conditions

The condition(s) this trial relates to.

osteoarthritis osteoarthritis, knee Patella Fracture

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OSTEOARTHRITIS, KNEE PATELLOFEMORAL KNEE ARTHROPLASTY

Contacts and locations

Locations

Aarhus University Hospital

Aarhus, Denmark

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