New daily pill could help millions shed pounds and control diabetes
NCT ID NCT06993792
First seen Nov 01, 2025 · Last updated May 01, 2026 · Updated 25 times
Summary
This large Phase 3 trial tests a once-daily tablet called orforglipron against a placebo in 1,200 adults who are obese or overweight, some of whom also have type 2 diabetes. The study aims to see if the drug helps with weight loss and is safe. Participants are split into two groups based on whether they have diabetes or not.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Accel Research Sites - DeLand Clinical Research Unit
DeLand, Florida, 32720, United States
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Accel Research Sites - NeuroStudies Clinical Research Unit
Decatur, Georgia, 30030, United States
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Activian Clinical Research
Kingwood, Texas, 77339, United States
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AmBeNet GmbH
Leipzig, 04107, Germany
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Biopharma Informatic, LLC
Houston, Texas, 77043, United States
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Boeson Research MSO
Missoula, Montana, 59804, United States
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CARE - Centro de Alergia y Enfermedades Respiratorias
Buenos Aires, 1414, Argentina
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CIPREC
Buenos Aires, C1119ACN, Argentina
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Care Access - Decatur
Decatur, Georgia, 30030, United States
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Care Access - Fayetteville
Fayetteville, North Carolina, 28314, United States
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Care Access - New Iberia
New Iberia, Louisiana, 70560, United States
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Care Access - Tampa
Tampa, Florida, 33625, United States
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Care Access - Thousand Oaks
Thousand Oaks, California, 91360, United States
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Centro Médico Viamonte
Buenos Aires, C1120AAC, Argentina
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Centro de Diagnóstico y Rehabilitación (CEDIR)
Santa Fe, 3000, Argentina
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Clinical Research Institute of Arizona (CRI) - Sun City West
Sun City West, Arizona, 85375, United States
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Clinical Research of Philadelphia
Philadelphia, Pennsylvania, 19114, United States
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Conquest Research
Winter Park, Florida, 32789, United States
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Consano Clinical Research, LLC
Shavano Park, Texas, 78231, United States
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Diabetes Zentrum Wilhelmsburg
Hamburg, 21109, Germany
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Donmed s.r.o.
Ostrava, 710 00, Czechia
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Encore Medical Research
Hollywood, Florida, 33024, United States
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Endocrine and Metabolic Consultants
Rockville, Maryland, 20852, United States
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Frontier Clinical Research, LLC
Smithfield, Pennsylvania, 15478, United States
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Fukuwa Clinic
Chūōku, 104-0031, Japan
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Gemeinschaftspraxis Dr. Taeschner/Dr. Bonigut
Leipzig, 04249, Germany
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Great Lakes Research Group, Inc.
Bay City, Michigan, 48706, United States
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Hasegawa Medicine Clinic
Chitose, 066-0032, Japan
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Indago Research & Health Center, Inc
Hialeah, Florida, 33012, United States
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InnoDiab Forschung Gmbh
Essen, 45136, Germany
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Innovation Medical Research Center - Fort Lauderdale
Fort Lauderdale, Florida, 33316, United States
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Instituto Centenario
CABA, 1204, Argentina
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Instituto Médico Catamarca IMEC
Rosario, 2000, Argentina
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Isis Clinical Research Center
Guaynabo, 00968, Puerto Rico
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Javara - Nevada Health Centers - Carson City
Carson City, Nevada, 89706, United States
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Javara - Privia Medical Group - Silver Spring
Silver Spring, Maryland, 20901, United States
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Javara - Privia Medical Group Georgia - Savannah
Savannah, Georgia, 31406, United States
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Javara - Tryon Medical Partners
Charlotte, North Carolina, 28210, United States
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Jinan Central Hospital
Jinan, 250013, China
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MUDr. Alena Vachova
České Budějovice, 37011, Czechia
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Medical Corporation Heishinkai OCROM Clinic
Suita-shi, 565-0853, Japan
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Medical Corporation Heishinkai ToCROM Clinic
Shinjuku-ku, 160-0008, Japan
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Medical Corporation Yuga Tsuruma Kaneshiro Diabetes Clinic
Yamato-shi, 242-0004, Japan
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Medical Plus
Uherské Hradiště, 686 01, Czechia
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Medicover Neuroendokrinologie
Munich, 81667, Germany
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Medizentrum Essen Borbeck
Essen, 45355, Germany
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Milan Kvapil s.r.o., Diabetologicka ambulance
Prague, 14900, Czechia
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Nemocnice Cesky Krumlov
Český Krumlov, 381 01, Czechia
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Norcal Endocrinology & Internal Medicine
San Ramon, California, 94583, United States
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Noritake Clinic
Ushiku, 300-1207, Japan
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North Georgia Clinical Research
Woodstock, Georgia, 30189, United States
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Novak Clinical Research - Tucson - North La Cholla Boulevard
Tucson, Arizona, 85741, United States
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Olive Takamatsu Medical Clinic
Takamatsu, 760-0076, Japan
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Peking University Third Hospital
Beijing, 100091, China
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Puerto Rico Health and Wellness Institute
Dorado, 00646, Puerto Rico
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RED-Institut GmbH
Oldenburg, 23758, Germany
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Shimokitazawa Tomo Clinic
Tokyo, 155-0031, Japan
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Sichuan Provincial People's Hospital
Chengdu, 610072, China
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Solaris Clinical Research
Meridian, Idaho, 83646, United States
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Southern California Clinical Research
Santa Ana, California, 92701, United States
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Texas Valley Clinical Research (TVCR) - Mission
Mission, Texas, 78572, United States
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The Corvallis Clinic, P.C.
Corvallis, Oregon, 97330, United States
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The First Affiliated Hospital of Henan University of Science &Technology
Luoyang Shi, 471003, China
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The Fourth Affiliated Hospital of Harbin Medical University
Harbin, 150001, China
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The Institute of Medical Science, Asahi Life Foundation
Chūōku, 103-0002, Japan
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The Machuca Foundation
Las Vegas, Nevada, 89101, United States
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The Second Affiliated Hospital Chongqing Medical University
Chongqing, 400010, China
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The Second Affiliated Hospital of Nanjing Medical University
Nanjing, 210011, China
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The Second Hospital of Tianjin Medical University
Tianjin, 300211, China
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The Second People's Hospital of Hefei
Hefei, 230011, China
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Tokuyama Clinic
Mihama-ku,Chiba City, 261-0004, Japan
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Tokyo-Eki Center-building Clinic
Chūōku, 103-0027, Japan
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Tsuchiura Medical & Health Care Center
Tsuchiura, 300-0012, Japan
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University of North Carolina Medical Center
Chapel Hill, North Carolina, 27514, United States
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Velocity Clinical Research, Dallas
Dallas, Texas, 75230, United States
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West Orange Endocrinology P.A.
Ocoee, Florida, 34761, United States
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Xuanwu Hospital Capital Medical University
Beijing, 100053, China
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Yokohama Minoru Clinic
Yokohama, 232-0064, Japan
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Zhongda Hospital Southeast University
Nanjing, 210009, China
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Zhujiang Hospital
Guangzhou, 510280, China
Conditions
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