New pill aims to tackle fatty liver and diabetes at once

NCT ID NCT05464784

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 2 trial tests an oral drug called MN-001 (tipelukast) in 40 adults with non-alcoholic fatty liver disease, type 2 diabetes, and high triglycerides. Participants take either the drug or a placebo daily for 24 weeks. The study measures changes in liver fat and blood fat levels to see if the drug is safe and effective.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

MN-001 (tipelukast)

What this could lead to

If it works, this could point toward a new oral treatment that reduces liver fat and triglycerides in people with fatty liver disease and diabetes.

What could go wrong

This is a small, early-phase trial with only 40 people. The drug may not show enough benefit or could cause side effects. Success in this trial does not guarantee approval.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

hypertriglyceridemia metabolic dysfunction-associated steatotic liver disease type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Jubilee Clinical Research, Inc.

    Las Vegas, Nevada, 89106, United States

  • Pinnacle Clinical Research at South Texas Research Institute

    Edinburg, Texas, 78539, United States