Could an antibiotic ease depression in people with obesity?

NCT ID NCT06537921

First seen Nov 17, 2025 · Last updated May 15, 2026 · Updated 21 times

Summary

This study tests whether adding the antibiotic minocycline to usual antidepressants can help people who have both obesity and treatment-resistant depression. Researchers believe that inflammation may play a role in these conditions, and minocycline can reduce inflammation. The study will enroll 35 adults with high inflammation levels and track how many complete the 8-week treatment and all study procedures.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • King's College London

    RECRUITING

    London, SE5 9RT, United Kingdom

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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