Migraine pills may calm your bladder too – new study
NCT ID NCT06212661
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study from the Cleveland Clinic is looking at whether certain migraine medications (CGRP inhibitors) can also improve bladder symptoms like urgency, frequency, and pain. About 200 women with hard-to-treat migraines and bladder issues will be followed for 3 months. Their symptoms will be compared to those getting Botox injections for migraines, to see if the CGRP drugs offer extra bladder benefits.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
CGRP inhibitors (gepants and monoclonal antibodies) and onabotulinumtoxinA (Botox) injections
What this could lead to
If successful, this could show that migraine medications also help bladder symptoms, pointing toward new treatment options for overactive bladder or bladder pain.
What could go wrong
This is an observational study, not a treatment trial, so it cannot prove cause and effect. Results may be small or not apply to everyone.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Cleveland Clinic, Main Campus
Cleveland, Ohio, 44195, United States