Migraine pills may calm your bladder too – new study
NCT ID NCT06212661
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study from the Cleveland Clinic is looking at whether certain migraine medications (CGRP inhibitors) can also improve bladder symptoms like urgency, frequency, and pain. About 200 women with hard-to-treat migraines and bladder issues will be followed for 3 months. Their symptoms will be compared to those getting Botox injections for migraines, to see if the CGRP drugs offer extra bladder benefits.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- CGRP inhibitors (gepants and monoclonal antibodies) and onabotulinumtoxinA (Botox) injections
- What this could lead to
- If successful, this could show that migraine medications also help bladder symptoms, pointing toward new treatment options for overactive bladder or bladder pain.
- What could go wrong
- This is an observational study, not a treatment trial, so it cannot prove cause and effect. Results may be small or not apply to everyone.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Cleveland Clinic, Main Campus
Cleveland, Ohio, 44195, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Could a symptom registry unmask hidden migraine variants?
- Can a nerve pain drug boost bladder pain relief?
- Melatonin may double up against childhood migraines