INTERSTITIAL CYSTITIS

This study tests whether injecting a substance made from donated amniotic membrane into the bladder can reduce pain and urgency in women with interstitial cystitis (painful bladder syndrome). One hundred women who have not gotten better with other treatments will receive either t…

This study tests whether giving patients a special nutritional drink (immunonutrition) before bladder removal surgery can reduce complications like infections. About 232 adults having open cystectomy for various bladder conditions will be randomly assigned to receive the drink or…

This study is testing whether a low-frequency pulsed electromagnetic field (PEMF) device can safely reduce pelvic pain and urinary symptoms in women with Interstitial Cystitis/Bladder Pain Syndrome. About 75 female adults will use the device at home, and researchers will track th…

This study tests a brief, 4-session cognitive behavioral therapy (CBT) program for people with urologic chronic pelvic pain syndrome (UCPPS), including interstitial cystitis and chronic prostatitis. The treatment is mostly home-based with minimal therapist contact, teaching skill…

This study looks at whether people with different types of bladder pain respond better to different treatments. About 220 adults with interstitial cystitis/bladder pain syndrome will receive either pelvic floor physical therapy or cognitive-behavioral therapy. The goal is to see …

This study tests a single dose of VNX001, a mix of lidocaine and heparin, to quickly reduce moderate to severe bladder pain in people with interstitial cystitis/bladder pain syndrome. About 120 adults with a history of IC/BPS for at least 9 months will receive either VNX001, plac…

This study tests a drug called VNX001 for people with Interstitial Cystitis (a painful bladder condition) who have sudden, moderate-to-severe bladder pain. About 50 adults will receive up to 6 doses of the drug directly into the bladder over 14 days. The goal is to see if the dru…

This study tests whether adding acupuncture to standard behavioral changes can better relieve bladder pain in women with interstitial cystitis. Thirty-four women who have not had prior treatments will receive either behavioral management alone or behavioral management plus weekly…

This study aims to find out if chronic pelvic pain conditions like prostatitis and interstitial cystitis can be inherited. Researchers will collect DNA and urine from 500 participants, including family members, to look for genetic links. The goal is to better understand the cause…

This study aims to find genetic factors that may cause interstitial cystitis (also called bladder pain syndrome). Researchers are collecting blood or saliva samples and medical information from 1,000 people with the condition and their family members across North America. No trea…