Could amniotic membrane ease bladder pain? new trial seeks answers
NCT ID NCT06096597
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether injecting a substance made from donated amniotic membrane into the bladder can reduce pain and urgency in women with interstitial cystitis (painful bladder syndrome). One hundred women who have not gotten better with other treatments will receive either the amniotic membrane injection or a placebo (salt water). The main goal is to see if symptoms improve significantly over time.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- micronized amniotic membrane (Clarix Flo)
- What this could lead to
- If it works, this could offer a new treatment option for women with painful bladder syndrome who haven't improved with other therapies.
- What could go wrong
- This is an early combined phase 2/3 trial with only 100 participants, so results may not be conclusive. The treatment is injected directly into the bladder, which carries risks of infection or discomfort.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for INTERSTITIAL CYSTITIS are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University Hospitals
RECRUITINGClevleand, Ohio, 44106, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Aloe vera concentrate put to the test against chronic bladder pain
- Could an antidepressant ease chronic bladder pain? new trial investigates
- Could a Low-Dose opioid blocker ease bladder pain?
- Ancient needle therapy takes on chronic bladder pain
- Could a magnetic helmet ease bladder pain? new study investigates
- Could your genes cause pelvic pain? new study seeks answers