Could amniotic membrane ease bladder pain? new trial seeks answers

NCT ID NCT06096597

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether injecting a substance made from donated amniotic membrane into the bladder can reduce pain and urgency in women with interstitial cystitis (painful bladder syndrome). One hundred women who have not gotten better with other treatments will receive either the amniotic membrane injection or a placebo (salt water). The main goal is to see if symptoms improve significantly over time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

micronized amniotic membrane (Clarix Flo)

What this could lead to

If it works, this could offer a new treatment option for women with painful bladder syndrome who haven't improved with other therapies.

What could go wrong

This is an early combined phase 2/3 trial with only 100 participants, so results may not be conclusive. The treatment is injected directly into the bladder, which carries risks of infection or discomfort.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

interstitial cystitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University Hospitals

    RECRUITING

    Clevleand, Ohio, 44106, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••