Could an antidepressant ease chronic bladder pain? new trial investigates
NCT ID NCT07698626
First seen Jul 13, 2026 · Last updated Jul 14, 2026 · Updated 1 time
Summary
This trial compares two approaches for adults with interstitial cystitis, a condition causing long-term bladder pain and frequent urination. All participants receive education and behavioral training, while half also take the antidepressant venlafaxine for 12 weeks. Researchers will track pain levels, urinary symptoms, sleep, and mood to see if adding the drug provides better relief. The goal is to find safer, more effective treatment options for this painful condition.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- venlafaxine
- What this could lead to
- If it works, this could offer a new treatment option for people with bladder pain syndrome, potentially improving pain and urinary symptoms with manageable side effects.
- What could go wrong
- This is an early-phase trial with only 140 participants, so results may not apply to everyone. Venlafaxine can cause side effects like nausea, dizziness, or sleep changes.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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