Diet over drugs: Low-Carb plan aims to improve sperm in obese men

NCT ID NCT06339840

Recruiting now Disease control Sponsor: Third Affiliated Hospital of Zhengzhou University Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a strict low-carbohydrate diet combined with lifestyle guidance can help obese men (BMI 30+) lose weight and improve their fertility. Researchers will track weight, semen quality, and reproductive outcomes in 98 men aged 22-40. The goal is to find a non-drug way to boost fertility in couples trying to conceive.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: low-carbohydrate diet with meal replacement
What this could lead to: If successful, this could show that a simple diet change improves sperm quality and fertility in obese men, offering a non-drug option.
What could go wrong: This is a small, early-stage trial with only 98 participants, so results may not apply to everyone. Diet adherence can be challenging, and fertility improvements are not guaranteed.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

male infertility Obesity obesity disorder Weight Loss

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ARTIFICIAL INSEMINATION IVF-ET MALE FERTILITY OBESITY WEIGHT LOSS

Contacts and locations

Locations

Third Affiliated Hospital of Zhengzhou University
RECRUITING

Zhengzhou, Henan, 450052, China

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