Could a seizure drug ease opioid-related pain in pancreatitis?
NCT ID NCT05603702
First seen Mar 18, 2026 · Last updated May 13, 2026 · Updated 6 times
Summary
This early-stage study tests whether adding lacosamide, a seizure medication, to standard opioid therapy is safe and tolerable for people with long-term abdominal pain from chronic pancreatitis. About 24 adults will take the drug for 7 days and be monitored for side effects and pain changes. The goal is to see if this combination can reduce a condition called opioid-induced hyperalgesia, where opioids actually make pain worse.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Indiana University
RECRUITINGIndianapolis, Indiana, 46202, United States
Contact
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Mayo Clinic
ACTIVE_NOT_RECRUITINGRochester, Minnesota, 55905, United States
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Ohio State University
ACTIVE_NOT_RECRUITINGColumbus, Ohio, 43210, United States
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Stanford University
ACTIVE_NOT_RECRUITINGStanford, California, 94305, United States
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University of Pittsburgh Medical Center
RECRUITINGPittsburgh, Pennsylvania, 15213, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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