New injection technique may offer better knee pain relief

NCT ID NCT05235854

Completed Symptom relief Sponsor: Centre Hospitalier Universitaire de Nīmes Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether injecting a steroid (betamethasone) directly into the torn meniscus of the knee provides better pain relief and function than the standard injection into the joint space. 70 people with stable degenerative meniscal tears were randomly assigned to one of the two injection methods. The main goal was to see if the targeted injection improved knee function scores more at 3 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Betamethasone (a corticosteroid)
What this could lead to: If it works, this could offer a more targeted, longer-lasting injection for knee pain from meniscal tears, possibly delaying or avoiding surgery.
What could go wrong: This is a small, early-phase study (70 people) comparing two injection methods. The benefit may be small or not last long, and steroids have risks like cartilage damage or infection.

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Conditions

The condition(s) this trial relates to.

osteoarthritis osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OSTEOARTHRITIS, KNEE

Contacts and locations

Locations

Chu Nimes

Nîmes, 30029, France

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