Kidney transplant may reverse heart damage, study hopes

NCT ID NCT07222683

Recruiting now Knowledge-focused Sponsor: Brigham and Women's Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study will follow 80 people with advanced chronic kidney disease who are waiting for a kidney transplant. Researchers will use PET scans and echocardiograms to measure blood flow and heart function before and after transplant. The goal is to see if improving kidney function and reducing inflammation can reverse early heart damage.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could show that kidney transplant improves heart blood flow and function, pointing toward ways to protect heart health in kidney disease patients.
What could go wrong: This is an observational study, not a treatment trial. It will measure changes but cannot prove cause and effect. Results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

chronic kidney disease chronic renal failure syndrome coronary artery disorder coronary microvascular disorder Inflammation inflammatory disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHRONIC KIDNEY DISEASE CORONARY MICROVASCULAR DYSFUNCTION (CMD) INFLAMMATION KIDNEY TRANSPLANT

Contacts and locations

Locations

Brigham and Women's Hospital
RECRUITING

Boston, Massachusetts, 02115, United States

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