Salt shield? study tests ketone supplement to lower blood pressure risks in seniors

NCT ID NCT06868719

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

Most older Americans eat too much salt, which can raise blood pressure and harm the kidneys. This study tests whether a ketone supplement (a substance the body makes during fasting or exercise) can block those harmful effects. Thirty-five adults aged 60-85 will follow a high-salt diet for 10 days, with or without the supplement, to see if it keeps blood pressure and blood vessel function healthy.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

ketone supplement (beta-hydroxybutyrate)

What this could lead to

If it works, this could point toward a simple supplement to help older adults counteract the negative effects of a high-salt diet without needing to drastically change what they eat.

What could go wrong

This is a very small, short-term pilot study (35 people, 10 days). It is not designed to prove long-term benefits or safety, and results may not apply to everyone. The supplement may not work as well in humans as it did in rodents.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cardiovascular disorder hypertensive disorder Inflammation inflammatory disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • School of Public Health

    RECRUITING

    Bloomington, Indiana, 47405, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••