Keto showdown: which fat is better for your heart and blood sugar?
NCT ID NCT05681468
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares two types of keto diets—one high in saturated fat and one high in unsaturated fat (like canola oil)—against a standard low-fat diet in 175 adults who are overweight or have prediabetes or type 2 diabetes. Researchers will measure changes in cholesterol, blood sugar, and inflammation over 6 months to see which diet offers the best heart and metabolic benefits. Participants receive nutrition counseling and are randomly assigned to one of the three diets.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
ketogenic diet (high fat, low carbohydrate) with either saturated or unsaturated fat sources, compared to a low-fat diet
What this could lead to
If successful, this study could show that a keto diet with healthy unsaturated fats is better for heart health and blood sugar control than a traditional keto or low-fat diet.
What could go wrong
This is a diet study, not a drug trial, so results depend heavily on participants sticking to the diet. It is also relatively small and short-term, so findings may not apply to everyone.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University of Alberta
RECRUITINGEdmonton, Alberta, T6G 2E1, Canada
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••