Scientists use drug to unravel Insulin's secrets in prediabetes
NCT ID NCT06354088
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at how the hormone insulin controls blood sugar and fat in healthy adults and those at risk for type 2 diabetes. Researchers will give participants a single dose of a drug called alpelisib, which blocks some of insulin's effects, to see if the liver can still make fat even when it stops responding to insulin's sugar-lowering signal. The goal is to better understand insulin resistance and related conditions like prediabetes and fatty liver disease.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Columbia University Irving Medical Center
RECRUITINGNew York, New York, 10032, United States
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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