Scientists use drug to unravel Insulin's secrets in prediabetes

This study looks at how the hormone insulin controls blood sugar and fat in healthy adults and those at risk for type 2 diabetes. Researchers will give participants a single dose of a drug called alpelisib, which blocks some of insulin's effects, to see if the liver can still make fat even when it stops responding to insulin's sugar-lowering signal. The goal is to better understand insulin resistance and related conditions like prediabetes and fatty liver disease.