Scientists use drug to unravel Insulin's secrets in the liver
NCT ID NCT06354088
First seen Dec 16, 2025 · Last updated May 16, 2026 · Updated 18 times
Summary
This study aims to understand how insulin controls sugar and fat production in the liver, comparing healthy adults to those at risk for type 2 diabetes. Participants will receive a single dose of the drug alpelisib or a placebo during two overnight hospital stays. Researchers will measure liver activity using special tracers to see how the body responds when insulin's effects are partially blocked.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Columbia University Irving Medical Center
RECRUITINGNew York, New York, 10032, United States
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