New heart pump trial aims to extend life for advanced heart failure patients

NCT ID NCT06526195

Recruiting now Disease control Sponsor: Abbott Medical Devices Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a mechanical heart pump (HeartMate 3) can help people with advanced heart failure live longer and avoid serious complications like stroke or the need for a heart transplant. About 850 participants will either receive the pump or continue standard medical therapy. The goal is to see if the pump improves survival and quality of life over two years.

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Conditions

The condition(s) this trial relates to.

advanced heart failure cardiovascular disorder heart disorder heart failure pulmonary hypertension

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CARDIOVASCULAR DISEASES HEART DISEASES HEART FAILURE PULMONARY HYPERTENSION

Contacts and locations

Locations

A.O.U. Citta della Salute e della Scienza di Torino
RECRUITING

Turin, Piedmont, 10126, Italy
AKH -Wien
RECRUITING

Vienna, State of Vienna, 1090, Austria
Abington Memorial Hospital
RECRUITING

Abington, Pennsylvania, 19001, United States
Advocate Health & Hospitals Corporation
RECRUITING

Oakbrook Terrace, Illinois, 60181, United States
Allegheny General Hospital
RECRUITING

Pittsburgh, Pennsylvania, 15212, United States
Ascension Texas Cardiovascular
RECRUITING

Austin, Texas, 78705, United States
Aurora Medical Group
RECRUITING

Milwaukee, Wisconsin, 53215, United States
Banner-University Medical Center Phoenix
RECRUITING

Phoenix, Arizona, 85006, United States
Baptist Health Medical Center
RECRUITING

Little Rock, Arkansas, 72205, United States
Baylor University Hospital
RECRUITING

Dallas, Texas, 75246, United States
CHI St. Luke's Health Baylor College of Medicine Medical Center
RECRUITING

Houston, Texas, 77030, United States
Carolinas Medical Center
RECRUITING

Charlotte, North Carolina, 28203, United States
Christ Hospital
RECRUITING

Cincinnati, Ohio, 45219, United States
Cleveland Clinic Florida
RECRUITING

Weston, Florida, 33331, United States
Deutsches Herzzentrum der Charité
RECRUITING

Berlin, State of Berlin, 13353, Germany
Erasmus MC - Thoraxcenter
RECRUITING

Rotterdam, Holland, 3015 CE, Netherlands
Hackensack University Medical Center
RECRUITING

Hackensack, New Jersey, 07601, United States
Henry Ford Hospital
RECRUITING

Detroit, Michigan, 48202, United States
Herzzentrum Leipzig GmbH
RECRUITING

Leipzig, Saxony, 04289, Germany
Houston Methodist
RECRUITING

Houston, Texas, 77030, United States
IKEM Prague
RECRUITING

Prague, CBohmia, 14021, Czechia
Integris Baptist Medical Center
RECRUITING

Oklahoma City, Oklahoma, 73112, United States
Kansas University Medical Center
RECRUITING

Kansas City, Kansas, 66160, United States
King Fahad Medical City
RECRUITING

Riyadh, Riyadh Region, 11525, Saudi Arabia
King Faisal Specialist Hospital
RECRUITING

Riyadh, Riyadh Region, 12713, Saudi Arabia
Maine Medical Center
RECRUITING

Portland, Maine, 04102, United States
Massachusetts General Hospital
RECRUITING

Boston, Massachusetts, 02114, United States
Mayo Clinic
RECRUITING

Rochester, Minnesota, 55905, United States
Medical University of South Carolina
RECRUITING

Charleston, South Carolina, 29425, United States
Medizinische Hochschule Hannover
RECRUITING

Hanover, Saxon, 30625, Germany
Minneapolis Heart Institute
RECRUITING

Minneapolis, Minnesota, 55407, United States
Montefiore Medical Center - Moses Campus
RECRUITING

The Bronx, New York, 10467, United States
New Mexico Heart Institute
RECRUITING

Albuquerque, New Mexico, 87102, United States
New York-Presbyterian/Columbia University Medical Center
RECRUITING

New York, New York, 10032, United States
Newark Beth Israel Medical Center
RECRUITING

Newark, New Jersey, 07112, United States
North Shore University Hospital
RECRUITING

Manhasset, New York, 11030, United States
Norton Hospital
RECRUITING

Louisville, Kentucky, 40202, United States
Oklahoma Heart Institute at Utica
RECRUITING

Tulsa, Oklahoma, 74104, United States
Oregon Health & Science University
RECRUITING

Portland, Oregon, 97239, United States
Penn State Milton S. Hershey Medical Center
RECRUITING

Hershey, Pennsylvania, 17033, United States
Piedmont Augusta Hospital
RECRUITING

Augusta, Georgia, 30901, United States
Piedmont Heart Institute
RECRUITING

Atlanta, Georgia, 30309, United States
Prisma Health Midlands
RECRUITING

Columbia, South Carolina, 29203, United States
Rigshospitalet
RECRUITING

Copenhagen, Copenhagen, 2100, Denmark
Saint Francis Hospital
RECRUITING

Tulsa, Oklahoma, 74136, United States
Scott & White Memorial Hospital
RECRUITING

Temple, Texas, 76508, United States
Shands at the University of Florida
RECRUITING

Gainesville, Florida, 32610, United States
Spectrum Health Butterworth Hospital
RECRUITING

Grand Rapids, Michigan, 49503, United States
St. Luke's Hospital
RECRUITING

Kansas City, Missouri, 64111, United States
St. Vincent Hospital
RECRUITING

Indianapolis, Indiana, 46240, United States
Sutter Medical Center
RECRUITING

Sacramento, California, 95816, United States
The Cleveland Clinic Foundation
RECRUITING

Cleveland, Ohio, 44195, United States
The Heart Hospital Baylor Plano
RECRUITING

Plano, Texas, 75093, United States
The Stern Cardiovascular Foundation
RECRUITING

Memphis, Tennessee, 38120, United States
UMC Utrecht
RECRUITING

Utrecht, Utrecht, 3584 CX, Netherlands
UTHealth Memorial Hermann
RECRUITING

Houston, Texas, 77030, United States
University of California at San Francisco
RECRUITING

San Francisco, California, 94143, United States
University of Chicago
RECRUITING

Chicago, Illinois, 60637, United States
University of Iowa Hospitals & Clinics
RECRUITING

Iowa City, Iowa, 52242, United States
University of Kentucky
RECRUITING

Lexington, Kentucky, 40536, United States
University of Nebraska Medical Center
RECRUITING

Omaha, Nebraska, 68198, United States
University of North Carolina at Chapel Hill
RECRUITING

Chapel Hill, North Carolina, 27599, United States
University of Pennsylvania
RECRUITING

Philadelphia, Pennsylvania, 19104, United States
University of Rochester Medical Center
RECRUITING

Rochester, New York, 14642, United States
University of Utah Hospital
RECRUITING

Salt Lake City, Utah, 84132, United States
University of Virginia Medical Center
RECRUITING

Charlottesville, Virginia, 22908, United States
Washington Hospital Center
RECRUITING

Washington D.C., District of Columbia, 20010, United States
WellStar Kennestone Hospital
RECRUITING

Marietta, Georgia, 30060, United States

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