Cold war on cancer: modified herpes virus takes on childhood brain tumors

NCT ID NCT03911388

First seen Feb 18, 2026 · Last updated Apr 25, 2026 · Updated 11 times

Summary

This early-stage trial tests whether a specially engineered herpes virus (G207) is safe for children whose cerebellar brain tumors have come back or not responded to standard treatments. The virus is injected directly into the tumor, and a small dose of radiation is given to help the virus work better. The study aims to find the safest dose and watch for side effects in up to 24 children aged 3 to 21.

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Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Children's of Alabama

    ACTIVE_NOT_RECRUITING

    Birmingham, Alabama, 35233, United States

  • MD Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • St. Louis Children's Hospital

    ACTIVE_NOT_RECRUITING

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.