NEOPLASM MALIGNANT
Clinical trials for NEOPLASM MALIGNANT explained in plain language.
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New hope for Hard-to-Treat cancers: targeted drug combo enters phase 2 trial
Disease control Recruiting nowThis phase 2 trial is testing a drug called calderasib (MK-1084), given alone or with cetuximab, in 150 people with advanced solid tumors that have a specific KRAS G12C mutation. The goal is to see if the cancer shrinks or disappears and to check for side effects. Participants mu…
Matched conditions: NEOPLASM MALIGNANT
Phase: PHASE2 • Sponsor: Merck Sharp & Dohme LLC • Aim: Disease control
Last updated Jun 27, 2026 14:01 UTC
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Killer virus turned against childhood brain cancer
Disease control Recruiting nowThis early-stage trial tests whether a specially engineered herpes virus (G207) is safe to inject directly into the brain tumors of children whose cancer has returned. Up to 24 children aged 3 to 21 will receive the virus, and some will also get a small dose of radiation to help …
Matched conditions: NEOPLASM MALIGNANT
Phase: PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 12:33 UTC
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Tumor samples used to create lab models for drug testing
Knowledge-focused Recruiting nowThis study takes tumor samples from 50 patients with specific gene mutations to grow tiny 3D cell clusters called spheroids in the lab. These spheroids help researchers test how well new or existing cancer drugs work against tumors with those mutations. The samples are collected …
Matched conditions: NEOPLASM MALIGNANT
Phase: NA • Sponsor: Centre Antoine Lacassagne • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC