Could a special supplement help obese patients shed pounds without losing muscle?

NCT ID NCT06309563

Recruiting now Disease control Sponsor: Istituto Auxologico Italiano Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether adding an essential amino acid supplement (EAA-AC) to a low-calorie, low-protein diet helps people with severe obesity lose weight while keeping muscle mass. Sixty participants aged 45-65 with a BMI over 35 will be randomly assigned to receive either the supplement or a placebo for two weeks. Researchers will measure weight loss, muscle changes, and blood sugar levels.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: essential amino acids and carboxylic acids (EAA-AC) supplement
What this could lead to: If successful, this could point toward a way to lose weight without losing muscle, improving overall health in severe obesity.
What could go wrong: This is a small, early-stage trial with only 60 participants over 2 weeks, so results may not apply widely. The supplement may not work better than diet alone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

morbid obesity Weight Loss

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OBESITY, MORBID WEIGHT LOSS

Contacts and locations

Locations

Istituto Auxologico Italiano, Site Piancavallo
RECRUITING

Oggebbio, Verbania, 28921, Italy

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