New drug cocktail trial aims to tame tough tumors

NCT ID NCT01552434

First seen Nov 01, 2025 · Last updated May 02, 2026 · Updated 29 times

Summary

This early-phase trial tests the safety and best dose of two drugs (bevacizumab and temsirolimus) given alone or with a third drug (valproic acid or cetuximab) in people with advanced cancers or certain non-cancerous but progressive diseases. The goal is to find tolerable doses and see if these combinations can slow or stop tumor growth. About 155 adults with hard-to-treat cancers or conditions like Castleman disease are participating.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for METASTATIC UROTHELIAL CARCINOMA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.