REFRACTORY MALIGNANT NEOPLASM

This early-stage trial aims to find safe doses and understand side effects of several drug combinations for patients with advanced cancers that haven't responded to standard treatments. The study involves 155 participants with various advanced or metastatic cancers and some rare …

This study is testing an oral medication called talazoparib for people with advanced cancers that have spread, returned, or stopped responding to standard treatments. It is specifically for patients whose cancers have certain genetic changes in the BRCA pathway (like BRCA1, BRCA2…

This early-stage study is testing the safety and best dose of combining standard chemotherapy drugs with a portable device that uses electrical fields to try to stop tumor growth. It is for patients whose cancer has spread to the liver and has not responded to other treatments. T…

This study is testing whether combining physical activity with a short course of the steroid dexamethasone can reduce severe fatigue in people with advanced cancer. It enrolled 90 participants to compare a high-dose steroid week with a low-dose steroid week, both alongside a 4-we…

This study aims to understand how common and severe financial distress is for people with advanced cancer. Researchers are asking 141 patients to complete short surveys about their financial situation, symptoms, and quality of life. The goal is to learn how the high cost of cance…