REFRACTORY MALIGNANT NEOPLASM
Clinical trials for REFRACTORY MALIGNANT NEOPLASM explained in plain language.
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New drug cocktail trial aims to tame tough tumors
Disease control OngoingThis early-phase trial tests the safety and best doses of two drugs (bevacizumab and temsirolimus) given alone or with other medicines (valproic acid or cetuximab) in people with advanced cancer or certain non-cancerous diseases that are hard to treat. The goal is to find the hig…
Matched conditions: REFRACTORY MALIGNANT NEOPLASM
Phase: PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 14, 2026 12:06 UTC
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Electric field device takes on liver tumors in early trial
Disease control OngoingThis early-phase study tests a portable device that creates electric fields to disrupt cancer cell growth, combined with chemotherapy and a targeted drug, in people whose cancer has spread to the liver and stopped responding to standard treatments. The main goal is to find the sa…
Matched conditions: REFRACTORY MALIGNANT NEOPLASM
Phase: PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 12, 2026 13:43 UTC
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New hope for tough cancers: drug targets BRCA mutations
Disease control OngoingThis study tests a drug called talazoparib in people with advanced cancers that have not responded to standard treatments. The drug works by blocking an enzyme that helps cancer cells survive, especially in tumors with changes in the BRCA genes or related DNA repair genes. The go…
Matched conditions: REFRACTORY MALIGNANT NEOPLASM
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 01, 2026 15:59 UTC
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Exercise plus steroid shows promise for cancer fatigue
Symptom relief OngoingThis study tests whether adding a short course of the steroid dexamethasone to a physical activity program can reduce severe fatigue in people with advanced cancer. About 90 participants will be randomly assigned to receive either a high or low dose of dexamethasone along with ex…
Matched conditions: REFRACTORY MALIGNANT NEOPLASM
Phase: PHASE2, PHASE3 • Sponsor: M.D. Anderson Cancer Center • Aim: Symptom relief
Last updated May 17, 2026 05:32 UTC
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Cancer's hidden cost: study reveals financial burden on patients
Knowledge-focused OngoingThis study looks at how serious money problems are for people with advanced cancer. Cancer care can be very expensive, and the stress from debt and high costs may make physical symptoms and quality of life worse. About 141 patients will fill out a short survey to measure their fi…
Matched conditions: REFRACTORY MALIGNANT NEOPLASM
Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated May 11, 2026 20:48 UTC