REFRACTORY MALIGNANT NEOPLASM
Clinical trials for REFRACTORY MALIGNANT NEOPLASM explained in plain language.
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Cancer drug targets BRCA mutations beyond breast and ovarian
Disease control OngoingThis phase 2 trial tests the drug talazoparib in 150 people with advanced cancers that have not responded to standard treatments. Participants must have specific gene changes in BRCA1, BRCA2, or related DNA repair genes. The drug works by blocking an enzyme that helps cancer cell…
Matched conditions: REFRACTORY MALIGNANT NEOPLASM
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 13:06 UTC
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Electric field device takes on liver tumors in early trial
Disease control OngoingThis early-phase study tests a portable device that sends gentle electric fields to the liver, combined with chemotherapy and a targeted drug (bevacizumab), in people whose cancer has spread to the liver and stopped responding to standard treatments. The main goal is to find the …
Matched conditions: REFRACTORY MALIGNANT NEOPLASM
Phase: PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 09:07 UTC
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Exercise plus steroid pill may fight cancer fatigue
Symptom relief OngoingThis study tests whether adding a short course of the steroid dexamethasone to a physical activity program can better reduce severe fatigue in people with advanced cancer. About 90 participants will be randomly assigned to receive either a high or low dose of dexamethasone along …
Matched conditions: REFRACTORY MALIGNANT NEOPLASM
Phase: PHASE2, PHASE3 • Sponsor: M.D. Anderson Cancer Center • Aim: Symptom relief
Last updated Jun 27, 2026 11:03 UTC
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Money worries weigh heavy on advanced cancer patients
Knowledge-focused OngoingThis study looks at how serious money problems are for people with advanced cancer. Researchers will survey 141 patients to measure financial distress and see if it is linked to their symptoms and quality of life. The goal is to understand the burden of cancer costs, not to test …
Matched conditions: REFRACTORY MALIGNANT NEOPLASM
Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:08 UTC