Can Weight-Loss surgery reverse severe fatty liver disease?

NCT ID NCT03472157

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests if weight-loss surgery is better than standard medical treatment for making nonalcoholic steatohepatitis (NASH) with advanced liver scarring disappear without making the scarring worse. It involves 100 obese adults with NASH and significant liver fibrosis. Participants are randomly assigned to either bariatric surgery or continued medical management, and the main goal is to see if NASH clears up on a liver biopsy.

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Conditions

The condition(s) this trial relates to.

cirrhosis of liver Fibrosis metabolic dysfunction-associated steatohepatitis metabolic dysfunction-associated steatotic liver disease Obesity obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Hôpital Claude Huriez, CHRU

    RECRUITING

    Lille, France

    Contact