New pill targets Cancer's 'Engine' in first human trial
NCT ID NCT07038369
First seen Nov 01, 2025 · Last updated Apr 10, 2026 · Updated 20 times
Summary
This is a first-in-human study to test the safety and find the right dose of an experimental pill called ATV-1601. It is for adults with advanced solid tumors, including certain breast, gynecologic, and prostate cancers, that have a specific genetic change called an AKT1 E17K mutation. The main goals are to see how the body processes the drug and what side effects it causes, while also looking for early signs that it might help control the cancer.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Centre Leon Berard
Lyon, 69008, France
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Florida Cancer Specialists & Research Institute - Lake Mary
Lake Mary, Florida, 32746, United States
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MD Anderson Cancer Center
Houston, Texas, 77030, United States
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Massachusetts General Hospital
Boston, Massachusetts, 02114, United States
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National Cancer Centre Singapore
Singapore, 168583, Singapore
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START Madrid - CIOCC
Madrid, 28050, Spain
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USC Norris Comprehensive Cancer Center
Los Angeles, California, 90033, United States
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Washington University
St Louis, Missouri, 63110, United States
Conditions
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