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Agreement of the estimated 1-Repetition-Maximum between two Multiple-Repetition-Maximum tests with different weight in patients with cardiovascular disease or risk factors

NCT ID NCT06796582

NEW Sponsor: Technical University of Munich Source: ClinicalTrials.gov ↗

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First seen Oct 22, 2026 · Last updated Oct 22, 2026

Summary

Exercise training is a cornerstone in the prevention and rehabilitation of cardiovascular disease. While research has primarily focused on endurance training, resistance training becomes more and more important. The gold standard to prescribe resistance training intensity or monitor longitudinal changes is the 1-Repetition-Maximum (1-RM) test. However, particularly for unexperienced individuals, this test may not be recommendable due to the high load and an increased risk of injuries. Alternatively, there are several published formulas to estimate the 1-RM based on a multiple-repetition-maximum (or repetition-to-failure) test. However, these formulas have been primarily tested in healthy individuals. Moreover, the reliability of the 1-RM estimation based on two tests with different submaximal weight is unknown. Therefore, the present study evaluates the agreement of the 1-RM estimation (based on different formulas) between two Multiple-RM tests with different weight in 50 patients with cardiovascular disease (heart failure, coronary heart disease, atrial fibrillation) or cardiovascular risk factors (type 2 diabetes, arterial hypertension).

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Study facts

What this study's own registry entry says, in plain language.

Participants

About 50 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jul 2025

Expected to finish

Feb 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients who visit the outpatient clinic for Preventive Sports Medicine and Sports Cardiology at the TUM University Hospital, Munich, Germany

Ages

50 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age ≥ 50 years * At least one of the following cardiovascular diseases / risk factors: * Heart failure * Coronary heart disease * Atrial fibrillation * Arterial hypertension * Type 2 diabetes mellitus * Clinically stable for ≥ 4 weeks * Medical clearance to perform resistance training / strength testing * Signed written informed consent Exclusion Criteria: * Pregnancy * Acute infection * Chronic joint inflammation * Knee, hip, ankle, wrist, elbow or shoulder pain * Known osteoporosis (T-value ≤ -2.5) * Uncontrolled hypertension (≥160 mmHG systolic / ≥100 mmHG diastolic) * Known cerebral or thoracic aneurysm

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Conditions

The condition(s) this trial relates to.

atrial fibrillation cardiovascular disorder coronary artery disorder Coronary Disease diabetes mellitus essential hypertension heart failure hypertensive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Arterial hypertension Atrial fibrillation (AF) Coronary heart disease (CHD) Diabetes mellitus Heart failure

How to take part

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  1. The places running it

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  2. The official record

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  3. A doctor treating you

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Contacts and locations

Locations

  • Department for Preventive Sports Medicine and Sports Cardiology, TUM Klinikum Rechts der Isar, Technical University of Munich

    RECRUITING

    München, 80809, Germany

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