CORONARY HEART DISEASE (CHD)

This study looks at whether taking just one blood thinner (a P2Y12 inhibitor) is as safe and effective as taking two blood thinners (dual antiplatelet therapy) for people with stable heart disease who have a drug-coated balloon procedure without a stent. About 2,170 adults will b…

This study is testing whether a community-based exercise program can improve exercise capacity in 200 adults aged 18-85 with reduced heart or lung function. Participants will exercise 40-60 minutes, five times a week, for eight weeks, doing activities like brisk walking, jogging,…

This study tests whether a new ultra-high resolution CT scanner is better than a standard CT at finding blocked arteries in the heart. About 140 adults with suspected coronary heart disease will get one scan, and the images will be compared to the usual method (catheterization). …

This study tests whether a brain-training technique called neurofeedback can help people with both heart disease and anxiety control their heart rate during stress. 56 adults will either receive real or fake (sham) neurofeedback while their brain activity and heart rate are measu…

This study tests whether a non-invasive brain-training technique called neurofeedback can help people with both coronary heart disease and anxiety. Participants will learn to control a part of their brain linked to stress, using real-time feedback from a headband. The goal is to …

This study will use a special camera (NIRS-OCT) to look inside the heart arteries of 1,516 people with diabetes. The goal is to find fatty plaques that might rupture and cause heart attacks. Researchers hope to create a new way to identify these dangerous plaques early, so doctor…

This study looks at why some people with coronary heart disease continue to have plaque buildup in their arteries even when they are on strong cholesterol-lowering medication. Researchers will follow 900 adults who have already had a heart procedure to see if leftover cholesterol…

This large study in China will enroll 12,000 heart disease patients who have had or will have a stent procedure (PCI). Researchers will collect blood samples, imaging, and health data to train an artificial intelligence system. The goal is to predict which patients are likely to …

This study is following 10,000 people hospitalized with confirmed or suspected coronary heart disease across multiple centers. Researchers are collecting detailed data on diagnoses, treatments, and outcomes to see which real-world strategies work best. The goal is to move away fr…

This study will follow 30,000 people aged 60 and older in rural China for up to 10 years. Researchers want to see if a comprehensive program—including medication, lifestyle changes, health education, and regular check-ups with a 7-day heart monitor—can lower the number of heart a…