Gene study aims to boost kidney transplant success for african americans
NCT ID NCT03615235
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
The APOLLO study looks at how variations in the APOL1 gene, common in people of African ancestry, affect kidney transplant outcomes. Researchers are testing DNA from 5,000 kidney donors and recipients to see if certain gene variants lead to faster kidney failure or harm living donors. The goal is to make transplants safer and more successful for this group.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this study could help doctors better match donors and recipients to improve kidney transplant survival and reduce risks for living donors.
What could go wrong
This is an observational study, not a treatment trial. It may not lead to immediate changes in care, and results depend on large-scale data collection.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for KIDNEY FAILURE are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Cleveland Clinic
Cleveland, Ohio, 44106, United States
-
Columbia University Irving Medical Center
New York, New York, 10032, United States
-
Duke University
Durham, North Carolina, 27705, United States
-
Emory University School of Medicine
Atlanta, Georgia, 30322, United States
-
Ichan School of Medicine at Mount Sinai
New York, New York, 10029, United States
-
Johns Hopkins University
Baltimore, Maryland, 21205, United States
-
Joslin Diabetes Center / Harvard University
Boston, Massachusetts, 02215, United States
-
Saint Louis University Center for Transplantation
St Louis, Missouri, 63104, United States
-
University of Alabama at Birmingham
Birmingham, Alabama, 35233, United States
-
University of California San Francisco
San Francisco, California, 94143, United States
-
University of Maryland School of Medicine
Baltimore, Maryland, 21201, United States
-
University of Miami / Miami Transplant Institute
Miami, Florida, 33133, United States
-
University of Michigan Medicine
Ann Arbor, Michigan, 48109, United States
-
University of Pennsylvania
Philadelphia, Pennsylvania, 19104, United States
-
University of Wisconsin - Madison
Madison, Wisconsin, 53792, United States
-
Vanderbilt University Medical Center
Nashville, Tennessee, 37232, United States
-
Wake Forest School of Medicine
Winston-Salem, North Carolina, 27157, United States
-
Weill Cornell Medicine
New York, New York, 10065, United States