Yale University
Clinical trials sponsored by Yale University, explained in plain language.
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New combo tackles brain tumors in melanoma and kidney cancer patients
Disease control TerminatedThis study tested a combination of two drugs, pembrolizumab and lenvatinib, in 18 adults with melanoma or kidney cancer that had spread to the brain. Participants had already received anti-PD-1/PD-L1 therapy. The goal was to see if the drug combo could shrink or eliminate brain t…
Phase: PHASE2 • Sponsor: Yale University • Aim: Disease control
Last updated Jun 16, 2026 12:50 UTC
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Heart drug digoxin fails to show promise for alcohol hepatitis in small trial
Disease control TerminatedThis study tested whether digoxin, a heart medication, could reduce inflammation in people with severe alcohol-related hepatitis. It enrolled 23 adults who were randomly assigned to receive digoxin or no digoxin for up to 28 days. The trial was terminated early, so results are li…
Phase: PHASE2 • Sponsor: Yale University • Aim: Disease control
Last updated Jun 15, 2026 19:05 UTC
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New alarm aims to end bedwetting: study tests effectiveness
Symptom relief TerminatedThis study tested a new bedwetting alarm called GoGoband against a standard alarm in children and young adults aged 6 to 21 with nighttime bedwetting. The goal was to see which device helped reduce wet nights more effectively. The study was stopped early and included only 16 part…
Phase: NA • Sponsor: Yale University • Aim: Symptom relief
Last updated May 27, 2026 23:05 UTC
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Brain zapping study reveals Memory's role in speech learning
Knowledge-focused TerminatedThis study looked at how memory for speech sounds and movements helps people learn to speak. Researchers used a gentle magnetic pulse to temporarily quiet a part of the brain linked to memory, then tested how well healthy adults could adjust their speech. The goal was to understa…
Phase: NA • Sponsor: Yale University • Aim: Knowledge-focused
Last updated Jun 16, 2026 18:16 UTC
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Brain zapping study sheds light on speech memory
Knowledge-focused TerminatedThis study aimed to understand which parts of the brain help us remember how to speak after learning new speech patterns. Researchers used magnetic pulses to temporarily quiet certain brain areas in healthy adults to see if it blocked memory retention. The study was terminated ea…
Phase: NA • Sponsor: Yale University • Aim: Knowledge-focused
Last updated Jun 15, 2026 19:07 UTC
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Can stretching skin change how you hear words?
Knowledge-focused TerminatedThis study looked at whether pairing touch sensations with speech sounds can change how people perceive speech. Researchers tested 160 right-handed adults with no known neurological issues. The study was terminated early, so results are limited.
Phase: NA • Sponsor: Yale University • Aim: Knowledge-focused
Last updated Jun 15, 2026 18:57 UTC
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Depression study halted after just one volunteer
Knowledge-focused TerminatedThis study aimed to see if a positive presentation before esketamine treatment could improve depression outcomes by boosting patient expectations. Only one person enrolled before the study was stopped. The goal was to measure how much of the treatment effect comes from non-specif…
Phase: NA • Sponsor: Yale University • Aim: Knowledge-focused
Last updated Jun 08, 2026 13:10 UTC
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Short Pre-Surgery exercise test may predict heart injury risk
Knowledge-focused TerminatedThis study looked at whether a brief exercise test before noncardiac surgery can help doctors detect heart injury after the operation better than standard care. Ten adults aged 45 and older took the test, had surgery, and had their heart monitored for injury. The goal was to see …
Phase: NA • Sponsor: Yale University • Aim: Knowledge-focused
Last updated Jun 01, 2026 17:58 UTC