University Of Southern California
Clinical trials sponsored by University Of Southern California, explained in plain language.
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New program aims to bridge critical gap for native americans facing cancer
Disease control Not yet recruitingThis study is creating and testing a culturally tailored patient navigation program designed to help American Indian and Alaska Native cancer patients in rural California get from diagnosis to treatment faster. The program, developed with community input, provides personalized su…
Phase: NA • Sponsor: University of Southern California • Aim: Disease control
Last updated Mar 25, 2026 14:09 UTC
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Sound waves for sight: early trial tests ultrasound to restore vision
Disease control Not yet recruitingThis early study is testing whether a wearable, non-invasive ultrasound device can safely stimulate nerve cells in the retina to help restore vision in people with age-related macular degeneration (AMD) or retinitis pigmentosa (RP). The goal is to develop a safer alternative to i…
Phase: NA • Sponsor: University of Southern California • Aim: Disease control
Last updated Mar 23, 2026 15:15 UTC
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New clinic aims to tackle heart failure and meth addiction at the same time
Disease control Not yet recruitingThis study is testing a new type of clinic that treats heart failure and methamphetamine addiction together. It will enroll 50 people with both conditions to see if combining heart care with addiction counseling and incentives can help them stop using meth and better manage their…
Phase: NA • Sponsor: University of Southern California • Aim: Disease control
Last updated Mar 16, 2026 15:26 UTC
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Could common heart meds be the key to stopping dementia before it starts?
Prevention Not yet recruitingThis small pilot study is testing whether carefully managing two common health issues—high blood pressure and high cholesterol—can help prevent dementia in people who are genetically at risk. It will enroll 10 adults aged 50-75 who carry a specific gene linked to higher dementia …
Phase: PHASE2 • Sponsor: University of Southern California • Aim: Prevention
Last updated Mar 31, 2026 12:11 UTC
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Could a common diabetes drug stop debilitating pregnancy sickness?
Prevention Not yet recruitingThis study is testing whether taking metformin, a medication commonly used for diabetes, before getting pregnant can help prevent severe nausea and vomiting (hyperemesis gravidarum) in women who experienced it in a previous pregnancy. Researchers will enroll 224 women aged 18-49 …
Phase: PHASE2 • Sponsor: University of Southern California • Aim: Prevention
Last updated Mar 30, 2026 14:32 UTC
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New ketamine pill tested for severe nerve pain relief
Symptom relief Not yet recruitingThis study is testing whether a new, long-acting ketamine tablet can reduce severe pain in adults with Complex Regional Pain Syndrome (CRPS). All 65 participants will take the tablets twice daily for 12 weeks, with doctors closely monitoring their pain levels and side effects. Th…
Phase: PHASE2 • Sponsor: University of Southern California • Aim: Symptom relief
Last updated Mar 30, 2026 14:31 UTC
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Your new therapist? study tests AI robot to boost anxiety treatment
Symptom relief Not yet recruitingThis study is testing whether a personalized, AI-driven robot companion can help college students with anxiety stick to their therapy homework. Researchers want to see if students are more motivated to complete daily Cognitive Behavioral Therapy (CBT) exercises when a robot provi…
Phase: NA • Sponsor: University of Southern California • Aim: Symptom relief
Last updated Mar 30, 2026 14:30 UTC
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Can a video call fix your voice? study tests online therapy for seniors
Symptom relief Not yet recruitingThis study is testing whether voice therapy for age-related voice problems works just as well when delivered through video calls (telehealth) as it does in person. Researchers will enroll 30 adults aged 55 and older and randomly assign them to receive four therapy sessions either…
Phase: NA • Sponsor: University of Southern California • Aim: Symptom relief
Last updated Mar 30, 2026 14:29 UTC
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Can a special diet pill and a workout supercharge your brain?
Knowledge-focused Not yet recruitingThis study aims to understand if taking a supplement to induce ketosis (a metabolic state) combined with exercise can increase a key brain chemical (BDNF) and improve thinking skills. It will specifically check if people with a certain genetic trait (the Met allele) benefit more.…
Phase: PHASE1 • Sponsor: University of Southern California • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:11 UTC
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Can a simple hearing aid help protect your brain?
Knowledge-focused Not yet recruitingThis small pilot study is checking if over-the-counter hearing aids are a practical and acceptable option for older adults who have a genetic risk for dementia and mild-to-moderate hearing loss. It will enroll 20 people aged 50+ to see if they can and will use the devices regular…
Phase: NA • Sponsor: University of Southern California • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:29 UTC
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Can a simple letter help ensure your wishes are heard?
Knowledge-focused Not yet recruitingThis study tests whether sending a mailer before a doctor's visit encourages older adults and people with serious illnesses to officially name a healthcare proxy—someone to make medical decisions if they cannot. Researchers will randomly assign 10,000 participants to either recei…
Phase: NA • Sponsor: University of Southern California • Aim: Knowledge-focused
Last updated Mar 20, 2026 14:48 UTC
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Cancer patients asked: would you try acupuncture or meditation?
Knowledge-focused Not yet recruitingThis study aims to understand if cancer patients are interested in adding complementary therapies like acupuncture, meditation, or massage to their standard cancer care. Researchers will survey 10 patients at USC Norris Cancer Center to learn about their current knowledge, attitu…
Sponsor: University of Southern California • Aim: Knowledge-focused
Last updated Mar 16, 2026 15:24 UTC
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AI steps in to help cancer patients navigate information maze
Knowledge-focused Not yet recruitingThis study aims to learn how patients with endometrial cancer currently find medical information about their care and how satisfied they are with those methods. It also wants to see if patients are interested in using an artificial intelligence (AI) tool for education. The resear…
Sponsor: University of Southern California • Aim: Knowledge-focused
Last updated Mar 13, 2026 15:06 UTC