New clinic aims to tackle heart failure and meth addiction at the same time

NCT ID NCT07211724

First seen Nov 01, 2025 · Last updated Jun 22, 2026 · Updated 30 times

Summary

This pilot study will test a clinic that treats both heart failure and methamphetamine use disorder together in 50 adults. Patients will receive heart failure medications and addiction counseling, plus incentives for staying meth-free. The goal is to see if this combined approach improves abstinence, medication use, and quality of life over 6 months.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Los Angeles General Medical Center

    Los Angeles, California, 90089, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of Southern California, Alfred E. Mann School of Pharmacy and Pharmaceutical Sciences

    Los Angeles, California, 90089, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

behavioral counseling, contingency management, and optional medications (mirtazapine, bupropion, naltrexone)

What this could lead to

If successful, this integrated care model could improve heart failure outcomes and methamphetamine abstinence in a high-risk group, potentially reducing hospitalizations and deaths.

What could go wrong

This is a small pilot study (50 people) with no control group, so results may not be generalizable. The intervention is complex and adherence may be low.

Conditions

The condition(s) this trial relates to.

heart failure methamphetamine dependence systolic heart failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.