New clinic aims to tackle heart failure and meth addiction together
NCT ID NCT07211724
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This pilot study will test a clinic that treats both heart failure and methamphetamine use disorder at the same time. Fifty adults with heart failure and active meth use will receive counseling, incentives for staying clean, and optional addiction medications, plus standard heart failure care. The goal is to see if this combined approach helps patients stay off meth and take their heart medications as prescribed over six months.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- behavioral counseling, contingency management, and optional medications (mirtazapine, bupropion, naltrexone)
- What this could lead to
- If successful, this integrated care model could improve heart failure outcomes and methamphetamine abstinence in a high-risk group, potentially reducing hospitalizations and deaths.
- What could go wrong
- This is a small, early pilot study with only 50 participants and no control group, so results may not apply broadly. The intervention is complex and may be difficult to sustain or scale.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Los Angeles General Medical Center
Los Angeles, California, 90089, United States
-
University of Southern California, Alfred E. Mann School of Pharmacy and Pharmaceutical Sciences
Los Angeles, California, 90089, United States
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