METHAMPHETAMINE USE DISORDER

This study tests whether a non-invasive brain stimulation technique can help veterans struggling with methamphetamine addiction. Researchers use magnetic pulses to target specific brain circuits involved in addiction and cravings. The goal is to reduce drug use and prevent relaps…

This small pilot study is testing whether a combination of non-invasive brain stimulation and a mental training technique can help people with methamphetamine addiction. Researchers will use a magnetic device on the scalp (rTMS) while participants practice vividly imagining posit…

This study is testing a new, non-invasive brain stimulation technique to help people with methamphetamine addiction. Researchers will use magnetic pulses on two specific brain areas to see if it can reduce drug cravings, improve flexible thinking, and lower the risk of relapse. T…

This early-stage study is testing whether a drug called troiluzole can help control methamphetamine use disorder by reducing cravings. It will involve 40 adults who currently use methamphetamine but are not seeking treatment. Researchers will measure if taking troiluzole makes pa…

This study is testing whether people with moderate to severe methamphetamine addiction can safely take a high-dose stimulant medication for 25 weeks alongside standard treatment. Researchers want to see if participants stay in the program, take their medication regularly, and are…

This study is testing whether a short, intensive brain stimulation treatment can help people with moderate to severe methamphetamine addiction. Researchers will give 20 participants either real or fake magnetic stimulation to the brain over 5 days during a brief hospital stay. Th…

This is a small, early-stage study to see if a single guided dose of psilocybin (the active compound in 'magic mushrooms') is safe and tolerable for people trying to quit methamphetamine. Researchers will recruit 20 people from a treatment center in Louisiana to see if the experi…

This early-stage study is testing whether a medication called pentoxifylline can reduce the rewarding effects of cocaine. It will involve about 30 adults with cocaine use disorder who are not currently seeking treatment. In a controlled lab setting, researchers will see if taking…

This study aims to understand how methamphetamine use affects heart health, especially in people who also experience psychosis. Researchers will compare heart electrical activity (ECG) in 240 people being treated for methamphetamine addiction, some with and some without psychosis…

This study aims to understand if specific proteins in the blood are linked to methamphetamine addiction and the psychosis it can sometimes cause. Researchers will compare blood levels of two proteins (LRFN5 and OLFM4) and markers of inflammation in 120 men: those with addiction, …

This study aims to understand the real health benefits people experience when they reduce their methamphetamine use, even if they don't quit completely. Researchers will measure physical and mental health improvements in 300 adults with methamphetamine use disorder over 12 weeks …