Zapping the brain to beat meth cravings: new trial launches

NCT ID NCT06457230

Recruiting now Disease control Sponsor: Shanghai Mental Health Center Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a new type of brain stimulation that sends paired pulses to the cerebellum and prefrontal cortex. The goal is to reduce cravings and improve cognitive flexibility in 90 adults with moderate to severe methamphetamine use disorder. Participants will receive either real or sham stimulation, and their cravings and thinking skills will be measured before and after treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: repetitive transcranial magnetic stimulation (rTMS) device
What this could lead to: If it works, this could offer a non-drug, brain-based therapy to help people with methamphetamine addiction reduce cravings and improve mental flexibility.
What could go wrong: This is an early-stage study with only 90 participants, so results may not apply to everyone. The treatment is experimental and may not reduce cravings or improve thinking as hoped.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

methamphetamine dependence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

METHAMPHETAMINE USE DISORDER

Contacts and locations

Locations

Min Zhao, PhD
RECRUITING

Shanghai, Shanghai Municipality, 200000, China

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Other studies related to the condition(s) this trial covers.