Could ketamine therapy help people quit meth?
NCT ID NCT06538285
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This pilot study tests whether combining ketamine injections with talk therapy is a safe and acceptable way to treat moderate-to-severe methamphetamine use disorder in 17 publicly insured patients, some of whom have or are at risk for HIV. Participants receive three monitored ketamine doses plus several therapy sessions, and report their meth use over three months. The goal is to see if this approach is feasible and tolerable, not yet to prove it works.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Ketamine (given as a shot) combined with talk therapy
What this could lead to
If this works, it could point toward a new treatment option for people with methamphetamine use disorder, especially those also at risk for HIV.
What could go wrong
This is a very small pilot study with only 17 participants, so results may not apply to everyone. Ketamine can cause side effects like high blood pressure or dissociation, and the therapy is intensive.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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San Francisco Department of Public Health
San Francicso, California, 94102, United States