Meth treatment study explores whether less use, not just no use, improves health

NCT ID NCT07226596

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether reducing methamphetamine use—without requiring complete abstinence—can improve health and quality of life. Researchers will give 300 adults with methamphetamine use disorder payments for providing drug-free urine samples over 12 weeks. They will measure blood pressure, sleep, and other health markers to see if less use leads to real benefits. The goal is to change how treatment success is measured, making it easier to develop new therapies.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Contingency Management (behavioral intervention with payments for negative urine samples)

What this could lead to

If successful, this could show that reducing methamphetamine use (not just quitting) is a valid treatment goal, leading to more flexible and accessible therapies.

What could go wrong

This is an early-stage behavioral study, not testing a drug. Results may not change current treatment standards, and participants may relapse after payments stop.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

methamphetamine dependence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Psychopharmacology of Addiction Laboratory

    RECRUITING

    Lexington, Kentucky, 40507, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••