University Of Michigan Rogel Cancer Center

This study tested a combination of two drugs, nivolumab and cabiralizumab, in 4 adults with a rare and aggressive blood cancer called peripheral T-cell lymphoma that had come back or not responded to prior treatments. The goal was to see if the drug pair could shrink tumors. The …

This study tested whether a potato-based starch supplement could reduce the risk of graft-versus-host disease (GVHD) in 107 people receiving stem cell transplants. GVHD occurs when donor immune cells attack the patient's body. The supplement is designed to increase butyrate, a gu…

This phase 2 trial tested whether giving an extra dose of radiation to the most resistant parts of a tumor, identified by a special MRI scan (DCE-MRI), could improve outcomes for people with advanced head and neck cancer. 106 participants received standard chemoradiation (cisplat…

This study tested a combination of an immunotherapy drug (nivolumab) and chemotherapy drugs (nanoliposomal-irinotecan, 5-fluorouracil, and leucovorin) in 34 people with advanced biliary tract cancer that had worsened after initial treatment. The goal was to see if the combo could…

This study tested whether adding the immunotherapy drug nivolumab to standard radiation and chemotherapy can help prevent cancer from returning in people with high-risk HPV-related throat cancer. The trial enrolled 26 participants with advanced-stage disease. Researchers measured…

This study tested whether adding focused radiation to standard hormone therapy or chemotherapy helps men with prostate cancer that has spread to a few spots (oligometastatic) and is no longer responding to hormone therapy alone. Fourteen participants received either standard trea…

This phase 2 pilot study tested the diabetes drug metformin in 37 people with chronic lymphocytic leukemia (CLL) that had come back after treatment, or in untreated CLL with a specific genetic change (11q deletion). The goal was to see if metformin could slow the cancer's growth.…

This early study tested a new radioactive tracer called [18F]3F-PHPG to see if it can help locate neuroendocrine tumors during PET scans. 32 adults with these tumors received the tracer and had two scans. The goal was to check image quality and how the tracer spreads in the body,…

This study looked at whether taking omeprazole (a heartburn drug) and low-dose aspirin together could help prevent colorectal polyps in people at high risk. Twenty-one adults with a history of multiple polyps took both pills daily for 25-45 days. Researchers collected tissue samp…

This study tested whether young cancer survivors (ages 15-39) could learn to do acupressure on themselves to reduce fatigue. 42 people who had finished cancer treatment at least three months ago and still felt tired took part. They used a special tool and a phone app to apply pre…

This study tested whether a simple at-home writing program could help teens and young adults (ages 15-39) who finished cancer treatment feel less distressed about their body image and reduce anxiety. Thirty survivors participated in a four-week expressive writing program. The goa…

This study looked at whether taking omega-3 fatty acid supplements can reduce joint pain and stiffness caused by aromatase inhibitors, a common hormone therapy for breast cancer. 77 postmenopausal women with early-stage breast cancer or at high risk took omega-3 supplements soon …

This study tested whether a mobile app called Roadmap 2.0 could improve the quality of life for caregivers and patients undergoing stem cell transplants. Over 370 caregivers and patients used a Fitbit tracker and answered surveys. Some also got the app with extra positive activit…

This study tested whether acupressure, a technique from Traditional Chinese Medicine, can ease fatigue in ovarian cancer survivors. 171 women who had completed primary cancer treatment were taught to apply pressure to specific points on their bodies daily for six weeks. The study…

This study tested a surgical procedure called RPNI to treat chronic pain after mastectomy. 26 participants who had pain for at least six months after surgery were enrolled. The approach aims to reduce pain, improve quality of life, and lower the need for painkillers by treating d…

This study tested whether self-acupressure—using fingers to press on specific points on the body—can reduce joint pain and stiffness caused by aromatase inhibitors, a common hormone therapy for breast cancer. Fifty postmenopausal women with breast cancer learned to do acupressure…

This study tested whether a new type of CT scan (dual energy CT) can produce clearer images of tumors during radiation therapy. Researchers compared the new scan to the standard scan in 30 adults receiving radiation for pelvic or genitourinary cancers. The goal was to see if the …

This study looked at whether a special website or coaching phone calls could help more people with a personal or family history of certain cancers get genetic testing. Over 800 participants were randomly assigned to one of these two methods or to standard care. The goal was to se…

This pilot study tested a web-based tool called MAP (Management of Active surveillance in Prostate Cancer) in 39 men aged 55+ with low-risk prostate cancer who were already on active surveillance. The tool provides education, helps coordinate care with primary care doctors, and o…

This pilot study tested a tool called CQUPLE, designed to help patients with low-risk thyroid cancer understand their treatment options and avoid overtreatment. Fifty patients were split into two groups: one received the CQUPLE decision aid and question list, while the other got …

This study tested a web-based program called GIFT that helps cancer patients share information about inherited cancer risks with their relatives. Over 3,000 patients and their family members took part. The goal was to see if the tool encourages more relatives to get genetic testi…