Can targeted radiation boost prostate cancer control?

NCT ID NCT03556904

Completed Disease control Sponsor: University of Michigan Rogel Cancer Center Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether adding focused radiation to standard hormone therapy or chemotherapy helps men with prostate cancer that has spread to a few spots (oligometastatic) and is no longer responding to hormone therapy alone. Fourteen participants received either standard treatment alone or standard treatment plus radiation. The goal was to see if the combination delays cancer growth or spread.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Ablative radiation therapy (focused radiation) plus standard hormone therapy or chemotherapy
What this could lead to: If successful, this could show that adding focused radiation to standard treatment helps control prostate cancer that has spread to a few spots, potentially delaying progression.
What could go wrong: This is a small, early-phase trial with only 14 participants, so results may not apply broadly. The added radiation may not improve outcomes and could cause side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for OLIGOMETASTATIC CASTRATION-RESISTANT PROSTATE CANCER are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

castration-resistant prostate carcinoma prostate cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PROSTATE CANCER

Contacts and locations

Locations

University of Michigan Cancer Center

Ann Arbor, Michigan, 48109, United States
VA Ann Arbor Healthcare System

Ann Arbor, Michigan, 48105, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.