University Of Alberta

This study tests whether a non-invasive breathing therapy can improve nerve repair in people with severe carpal tunnel syndrome. Participants will breathe alternating cycles of regular air and low-oxygen air, which may help nerves regenerate. The goal is to improve hand function …

This study tests whether pharmacists can help people lower their risk of heart disease. Over 1,000 adults with conditions like diabetes, high blood pressure, or obesity will receive pharmacist-led support. The goal is to see if this approach reduces overall cardiovascular risk wi…

This study looks at whether extra check-ups and early help from a team of specialists—like nurses, dietitians, and exercise therapists—can reduce heart problems in people being treated for breast cancer. About 80 adults receiving certain chemotherapy drugs will be randomly assign…

This study tests whether vasopressin works better than the standard drug epinephrine during CPR for newborns with no heartbeat or very low heart rate. Researchers will compare how quickly the heart recovers and whether babies survive without brain injury. Only 8 infants are enrol…

This study looks at whether people with stable heart disease (but without heart failure or irregular heartbeat) can safely stop taking beta-blockers. Researchers will compare those who continue the drug versus those who stop, tracking heart attacks, hospitalizations, and death ov…

This study tests whether women with high blood pressure can better control it by measuring their blood pressure at home and sharing results with a pharmacist every four weeks. About 368 women will either receive a home monitor and regular pharmacist follow-up or standard care. Th…

This study tests a program that gives kidney failure patients extra support to find a living donor for a transplant. The program helps patients talk to family and friends about donation. The goal is to see if this support leads to more living donor kidney transplants.

This study looks at whether reducing the number and dose of medications can improve health for people aged 80 and older who take 6 or more daily pills. Doctors and nurse practitioners will work with patients to safely lower doses or stop unnecessary drugs. The goal is to see if t…

This study compares three different PET/CT scans (68Ga-HA-DOTATATE, 18F-DOPA, and 18F-FDG) in 50 adults with metastatic neuroendocrine tumors. The goal is to see which scan best detects all tumor spots and whether different scans show different results. Findings may help doctors …

This study looks at whether a simple mobile app can help breast cancer survivors exercise more after finishing treatment. About 200 people will either use the app for 12 weeks or get standard exercise guidelines. The goal is to see if the app reduces fatigue, improves physical fu…

This small pilot study tests whether an inhaled drug called Treprostinil can reduce breathlessness and improve exercise ability in people with mild COPD. Twenty participants will undergo lung function tests, exercise tests, heart ultrasound, and CT scans over several visits. The …

This pilot study tests whether a combination of relaxation, guided imagery, and gentle massage can help prevent delirium in critically ill patients in the intensive care unit (ICU). Delirium is a state of confusion that can make recovery harder. The study involves 120 adults in t…

This study tests whether a gentle electrical stimulation called TENS can reduce muscle spasticity and improve movement control in people with spinal cord injury. Forty adults with injuries between C5 and T12 will either receive TENS right away or after a two-month wait. Researche…

This study aimed to see if a mild electrical brain stimulation called tDCS could help people with severe depression that didn't improve after many other treatments. Participants would have received either real or fake stimulation alongside their usual care. However, the study was…

This study compares 3 months of intensive leg exercise to standard physical therapy in 60 young children with spastic diplegia caused by prematurity. The goal is to see if the extra leg work improves gross motor function and quality of life. Children must be able to stand with so…

This study looks at whether giving Cutaquig® (a medicine that helps fight infections) through a faster, manual push method is safe and comfortable for adults with primary or secondary immune deficiencies. About 36 participants will try this method at home. The goal is to see if t…

This study tests a small, home-use device that sends gentle electrical pulses to the belly to help people with chronic spinal cord injury empty their bowels faster. Twelve participants will use the device for 30 minutes before each bowel routine over two months. Researchers will …

This study tests a simple bedside exercise program called BE-FIT for older adults (65+) after surgery. The goal is to get patients out of bed and moving earlier to prevent muscle loss, falls, and longer hospital stays. About 2,180 participants will either follow the exercise plan…

This study follows 750 adults with small kidney tumors who are not good candidates for surgery. Researchers will track how well freezing (cryotherapy) or burning (radiofrequency ablation) works over time, including cancer survival, kidney function, and complications. Blood and ur…

This study looks at 20 adults who recently had a stroke to compare two types of brain scans: CT and PET. The goal is to see how well PET scans measure blood flow and brain cell activity compared to standard CT scans. Participants will get both scans within a week of their stroke,…

This study tests a program that gives personalized support to people with kidney failure who need a transplant. The goal is to help them find a living donor from their family or friends. 66 participants will receive guidance from a team of experts to learn how to talk about donat…

This study was designed to test whether a specific exercise program could help nerves regrow faster and restore muscle and bone health in adults with brachial plexus injury (nerve damage in the shoulder/arm). The plan was to enroll 18- to 60-year-olds who had nerve transfer surge…

This study looks back at the records of over 46,000 diabetic patients who had surgery in Alberta, Canada. The goal is to see how often their long-term blood sugar (HbA1C) was checked before the operation and whether poor control leads to complications. By understanding current pr…

This study looks at whether giving families extra support—like help with parking and encouraging text messages—can reduce dropout rates in pediatric obesity treatment. About 108 children aged 6 to 17 will be randomly assigned to receive either usual care alone or usual care plus …

This study follows 1500 people with pituitary gland disorders to see how they do over time, whether treated with medication, surgery, or just monitoring. Researchers want to learn what factors predict tumor regrowth after surgery. The goal is to gather knowledge, not to test a ne…

This study looks at whether a program of strength exercises and reducing sitting time before elective surgery can help frail patients recover more quickly. Researchers will measure walking speed, physical activity, and complications after surgery. The study includes 50 adults age…

This study tests whether online infographic modules (KIDCLOT) help children on blood thinners and their families understand their treatment better. About 248 pediatric patients and caregivers will use the modules and take quizzes to measure learning. The goal is to see if this mo…

This study looks at how multiple sclerosis (MS) symptoms, like fatigue and thinking problems, change during different times of the menstrual cycle. About 300 females with MS will track their symptoms and cycle using a phone app for six months. The goal is to find patterns that co…