Tiny trial tests vasopressin to save Newborns' hearts

NCT ID NCT05738148

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares vasopressin to the standard drug epinephrine for newborns who need CPR at birth. Only 8 babies were enrolled, and the hospital was randomly assigned to use one drug for a year. The goal is to see which drug helps restart the heart faster, but the results are very preliminary.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Vasopressin

What this could lead to

If vasopressin works better than epinephrine, it could offer a new option to restart a newborn's heart during CPR.

What could go wrong

This is a tiny phase 1 trial with only 8 babies, so it cannot prove safety or effectiveness. The results may not apply to all newborns.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cardiac arrest

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Royal Alexandra Hospital

    Edmonton, Alberta, T5H 3V9, Canada