University Hospital, Brest

This study compared two surgical techniques to repair damaged knee cartilage in 58 adults aged 18-50. One method uses a patient's own cartilage cells grown in a lab, while the other uses small plugs of healthy cartilage from another part of the knee. The goal was to see which app…

This study tested a personalized approach to giving fluids to people with septic shock, using small fluid challenges to guide treatment. The goal was to reduce organ failure by avoiding both too little and too much fluid. Over 500 adults in intensive care took part, and the appro…

This study looked at 22 adults with type 1 diabetes who use an insulin pump. It compared taking a fast-acting insulin (insulin aspart) just before a meal versus right after a meal. The goal was to see which timing leads to better blood sugar control over 14 days. The study measur…

This study looked at 45 patients whose HPV tests came back negative but had a late signal in the raw data. Researchers wanted to see if these late signals might actually indicate early cervical cell changes. By comparing different lab methods, they aim to improve how we interpret…

This study tested two new devices that automatically measure vision in children aged 6 to 16. The devices use special lenses that adjust themselves, avoiding the need for eye drops that dilate the pupils. Researchers compared the results from 43 children to the standard dilation …

This study looked at whether a new DNA-based method called shotgun metagenomics can better diagnose chronic infections in artificial joints compared to standard lab cultures. Researchers tested 144 adults who needed surgery for a suspected joint infection. The goal was to see if …

This study tested whether a special PET/CT scan (V/Q PET/CT) can accurately diagnose pulmonary embolism (a blood clot in the lungs) compared to the standard CT scan. About 100 adults with suspected first-time clots took part. The goal was to see how sensitive and specific the new…

This study tested a new CT scan method that creates a map of blood flow in the lungs to diagnose pulmonary embolism (blood clots). Researchers compared it to the standard SPECT scan in 30 patients. The goal was to see if the new method is as accurate, while being faster and safer…

This study tested whether a French translation of the HSCL25 questionnaire can help general practitioners accurately diagnose depression in adults visiting primary care. Over 1,100 participants completed the questionnaire, and their scores were compared to a standard diagnostic i…

This study tested whether a system where caregivers send text messages to people who have survived a suicide attempt could help prevent future attempts. Fifteen adults who were hospitalized after a suicide attempt took part. The main goal was to see if patients and caregivers fou…

This study looked at whether using intermittent pneumatic compression (IPC) devices on the legs, along with elastic stockings, reduces blood clots better than stockings alone in intensive care patients who are at high risk of bleeding. About 408 adults in ICUs with conditions lik…

This study tested two oral medications, aprepitant and hydroxyzine, to see which better reduces severe itching triggered by water contact in people with myeloproliferative neoplasms (a type of blood cancer). 63 participants who had persistent itching rated 5 or higher on a 10-poi…

This study tested whether methoxyflurane (Penthrox®), a pain-relief inhaler used for trauma, can quickly reduce pain in adults with dental emergencies. 190 participants received either the drug or a placebo. The goal was to see if it lowers pain within 15 minutes, offering a fast…

This study tested if LED light therapy can help people with sensitive skin who do not have other skin diseases like rosacea or acne. Thirty adults with sensitive skin received the treatment, and researchers measured changes in symptoms like pain and itching. The goal was to see i…

This study looked at two simple, drug-free ways to ease pain in newborns during a needle stick: breastfeeding or a sugar solution. Researchers measured brain activity and stress levels in 114 healthy, full-term breastfed babies. The goal was to see which method works better for c…

This study tested whether giving two types of light therapy (intense pulsed light and low-level light therapy) before laser eye surgery can help prevent dry eyes afterward. 62 people who were already scheduled for laser vision correction took part. The goal was to see if these tr…

This study tested a smartphone app called "Bouge" to see if it could help pregnant women walk more. 250 women in early pregnancy used the app to track their steps. The goal was to increase daily steps by 2,000 over 90 days. The study also looked at sleep, well-being, and back pai…

This study tested whether using a non-invasive breathing mask (like a CPAP machine) for at least 7 days before lung cancer surgery could reduce serious heart and lung complications. The trial included 300 adults with lung cancer who also had breathing problems, obesity, or heart …

This study tested an early, intensive therapy program called HABIT-ILE in 36 children aged 1 to 4 years with bilateral cerebral palsy. The therapy focuses on structured, repetitive exercises for both arms and legs to improve motor function and daily activities. Researchers measur…

This study looked at whether adding special breathing muscle training to a standard 3-week lung rehab program helps reduce shortness of breath in people with COPD. The 38 participants all had normal breathing muscle strength. The goal was to see if the combined approach works bet…

This study tested two methods to strengthen leg muscles in 102 people with severe COPD: electrical stimulation (using pads on the skin) and stationary cycling. Both were part of a 3-4 week hospital rehab program. The goal was to see which better improves leg function and exercise…

This study tested whether the drug oxybutynin can reduce excessive sweating (hyperhidrosis) in adults. 62 participants received either oxybutynin or a placebo. The main goal was to see if the drug improves sweating severity and quality of life, while also checking for side effect…

This study looked back at 170 adults with a serious eye infection called endophthalmitis to see if early surgery (within 48 hours) helps vision more than starting with medicine alone. Researchers compared how well people could see one month after treatment. The goal is to find ou…

This study looked at 176 COPD patients to see if performing two 6-minute walk tests at the end of a 4-week pulmonary rehabilitation program gives a more accurate measure of their exercise capacity. Current guidelines usually recommend only one test, but newer research suggests a …

This study looked at 70 people with myeloma or lymphoma who needed a stem cell transplant. Researchers compared two drugs, Zarzio and Granocyte, used to help collect enough stem cells for the transplant. The goal was to see which drug worked better for getting a good graft.

This study looked at how body measurements, shoulder muscle strength, and core endurance influence a common shoulder stability test. 247 healthy adults aged 18 to 50 performed a push-up style test while researchers measured their strength and endurance. The goal was to better und…

This study looked at whether special rocker sole shoes change balance in people with type 2 diabetes who have nerve damage in their feet. 25 adults aged 18 to 75 who could walk without help took part. Researchers measured how much their body swayed while standing still in the spe…

This study looked at 116 kidney transplant patients to understand how certain immune cells (B cells) contribute to organ rejection. Researchers analyzed blood samples to find patterns that might predict rejection before it happens. The goal is to improve future treatments, not to…

This study looked at 200 women who have given birth to see if a full bladder changes the angle of the uterus. The goal is to make inserting IUDs (a type of birth control) less painful and easier for doctors. Participants had ultrasound measurements with both a full and empty blad…

This study looked at how the blood thinner rivaroxaban acts in people with severe obesity and in those who had weight-loss surgery (gastric bypass or sleeve gastrectomy) at least a year earlier. Sixty-seven participants took rivaroxaban for eight days, and researchers measured dr…

This study looked at how well young handball players can adjust their sense of balance (proprioception) during sudden movements. Researchers measured knee forces in 41 athletes aged 15-25 during cutting and jumping tasks. The goal was to understand if poor balance adjustment incr…

This study tested a portable ultrasound device that measures pelvic tilt in healthy volunteers and patients undergoing hip replacement. Researchers wanted to see if the device gives consistent results when different operators use it. They also measured how pelvic tilt changes bef…

This study examined how two different induction drugs (thymoglobulin and basiliximab) affect B cells—a type of immune cell—in 49 kidney transplant recipients. Researchers compared B cell profiles shortly after transplant to better understand immune responses. The goal was to gath…

This study looked at 750 people hospitalized for a COPD flare-up to find out how many also had a pulmonary embolism (a blood clot in the lung). Doctors used a standard set of tests, including a blood test and special scans, to check for clots. Participants were followed for 3 mon…

This study looked at whether a special scan (PET/CT) done within two months after treatment helps doctors make better decisions for patients with advanced cervical cancer. Researchers compared what doctors would decide without the scan versus with it. The goal was to see if the s…

This study looked at whether a six-minute stepper test (ST6) can show improvements in exercise tolerance for people with COPD after a 3-week pulmonary rehabilitation program. 72 participants with all stages of COPD took part. The goal was to see if the number of steps changed bef…

This study involved 82 healthy young adults aged 18 to 25. Researchers measured how body size and physical activity levels affect a test of shoulder stability called the CKCUEST. No treatment was given; the goal was simply to gather information.

This study aimed to find the normal size of the ulnar nerve at the elbow using ultrasound in 50 healthy adults without any nerve problems. Researchers measured the nerve's surface area to establish a standard reference range. The results help doctors better diagnose ulnar nerve i…