University Hospital, Basel, Switzerland

This study looked at 10,000 people who came to the emergency room with chest pain. The goal was to see if new blood tests could help doctors find heart attacks faster than current methods. Researchers compared these new markers with the standard test to see which worked best for …

This study tested whether a special CT scan done in the procedure room can accurately detect bleeding in the brain of stroke patients. The goal is to speed up diagnosis and treatment by avoiding extra trips to the regular CT scanner. 252 adults with stroke symptoms were enrolled …

This study tested a drug called conestat alfa in 141 people undergoing a minimally invasive heart valve replacement (TAVI) for severe aortic stenosis. The goal was to see if the drug could reduce the risk of small strokes and kidney damage that can happen after the procedure. Par…

This study tested whether GLP-1 medicines (like Ozempic) can improve sexual desire in overweight or obese adults. 85 men and women took the drug plus made lifestyle changes, or only changed their lifestyle. Researchers measured changes in sexual thoughts, activity, and desire usi…

This study tested a 12-session outdoor group training program where children interacted with animals to build resilience. It included 107 children aged 2-4 or 8-12 who had either autism or a history of stressful life events. The goal was to see if this approach could help them be…

This study tested whether using a smartphone app alongside standard physiotherapy helps people with low back pain more than physiotherapy alone. Sixty adults with low back pain lasting at least six weeks took part. Researchers measured changes in disability and pain levels to see…

This completed study looked at how a single dose of semaglutide (a diabetes drug) affects cortisol and other stress hormones in 22 healthy men. Researchers compared the hormone changes after taking the drug versus a placebo. The goal was purely to understand the body's response, …

This study explores whether mannitol, a sugar alcohol, can trigger the release of copeptin, a hormone marker, to help diagnose polyuria-polydipsia syndrome (excessive thirst and urination). In part 1, healthy adults receive mannitol or placebo to see if copeptin rises. In part 2,…

This study looked at whether giving ketanserin, olanzapine, or lorazepam after taking LSD can make the experience shorter or less intense. Twenty healthy adults took LSD alone or with one of these drugs, and researchers measured their feelings and perceptions. The goal is to lear…

This study looked at how daylight and physical activity influence the body's internal clock and sleep. Fifty-one healthy adults aged 18-35 were exposed to different lighting conditions (office light, natural daylight, or daylight with blue-light-blocking glasses) and either reste…

This study looked at whether activity sensors can be easily used in hospitals to track how much patients move. 19 hospitalized adults who could walk but were on bed rest wore the sensors. Researchers measured how much extra time staff needed to use the sensors and how comfortable…

This study looked at whether brown fat helps the body handle nutrients from food better. Researchers compared 30 volunteers with and without active brown fat, giving them separate meals of protein, fat, and carbs. They measured blood markers and energy use to see how brown fat af…

This study looked at how routine cleft repair surgery changes blood flow in the roof of the mouth. Researchers used a non-invasive probe to measure oxygen levels in the tissue before and after surgery in 77 patients. The goal was to understand the surgery's effect on tissue healt…

This study reviewed medical records of 800 adult ICU patients to see if the length of EEG brain monitoring changes how doctors diagnose and treat neurological problems. Researchers collected data on patient history, test results, and outcomes. The goal was to learn more, not to t…

This completed Phase 1 study involved 26 healthy volunteers to compare the immediate effects of two forms of MDMA: R-MDMA and S-MDMA. Researchers measured subjective feelings like mood and empathy, as well as physical responses like blood pressure and heart rate. The goal was to …

This study looked at 1,000 women who had breast reconstruction with implants right after mastectomy and also received radiation therapy. Researchers compared two implant types—polyurethane-coated and non-polyurethane-coated—to see which had fewer problems like scarring (capsular …

This study used artificial intelligence to predict how engaged people would be in online therapy and how much their symptoms would improve. Researchers analyzed data from over 6,600 adults who took part in a digital psychotherapy program. The goal was to create fair AI tools that…

This study looked at whether interleukin-6 (a protein involved in inflammation) affects how glucagon (a hormone) lowers amino acid levels in the blood. 26 healthy adults received either a dummy infusion or a drug that blocks interleukin-6, then had their amino acid and hormone le…

This study tested whether artificial intelligence (AI) can realistically simulate conversations between a therapist and a person with a mental health problem. Researchers used 520 simulated sessions to see if the AI could follow proper therapy techniques. The goal is to use these…

This study looked at whether DMT, a psychedelic drug, can reduce pain in healthy adults. Seventeen participants received DMT, ketamine, or a placebo, and their pain responses to mild electrical shocks were measured. The goal was to see if DMT has pain-relieving effects, which cou…

This study looked at how much waste is created during heart procedures like angiograms and valve repairs. Researchers weighed and sorted trash from 40 procedures into paper, regular waste, medical waste, and recyclable plastic. They then compared two waste-handling methods to see…

This study looked at how low doses of LSD change the way healthy adults make decisions based on what they see. Thirty participants completed computer tasks that tested their ability to predict and respond to visual patterns. The goal was to understand how LSD influences brain sig…

This study looked at how healthy aging changes the body's ability to manage water levels. Researchers measured a substance called copeptin in 32 healthy adults—both older (60+) and younger (18-30)—after giving them salty water or plain water. The goal was to understand why older …