University Hospital, Basel, Switzerland

This early-stage trial tests a new type of CAR T cell therapy that targets two proteins (CD19 and CD20) on cancer cells. It is for adults with B cell leukemia or lymphoma who have run out of standard options, including commercial CAR T cells. The main goal is to check the safety …

This study aims to see if a new test using mannitol can diagnose the cause of excessive thirst and urination as accurately as the current standard test. About 144 adults with these symptoms will take both tests and share which they prefer. The goal is to find a simpler, more pati…

This study tests a new program where trained village health workers use tablet-based tools to provide HIV prevention services, including PrEP and emergency PEP, to people at high risk in rural Lesotho. About 380 participants will be enrolled to see if this approach increases mont…

This study tests whether an IDO-1 inhibitor can safely prevent Epstein-Barr virus (EBV) complications in kidney transplant patients who have never had EBV but receive a kidney from a donor who has. Nine participants will receive either the drug or a placebo alongside standard car…

This study tests whether giving a low dose of lorazepam (a sedative) early on can prevent delirium (severe confusion) in intensive care patients who are at higher risk due to heavy alcohol use. Researchers will use a blood test called the Anttila-Index to identify these patients …

This study looks at whether the sensory experience of eating (taste, smell, chewing) influences how much energy the body uses to digest a meal. Twenty-four healthy adults will eat the same meal in two ways: normally by mouth and directly into the stomach via a tube. Researchers w…

This pilot study tests a simple method to find and treat lymphatic injuries during groin vascular surgery. Researchers will check if this approach reduces wound complications like fluid buildup, leaks, or infections. The study involves 60 adults having groin surgery and aims to g…

This study gives a single dose of MDMA or a placebo to 40 adults (20 with autism and 20 matched healthy controls) to see how their bodies release oxytocin, a hormone linked to social bonding. The goal is not to treat autism but to understand if the oxytocin system works different…

This study compares a 3-step hand rub technique to the standard 6-step method recommended by the World Health Organization. Researchers want to see if a simpler method helps healthcare workers clean their hands more often and more thoroughly. About 40 hospital workers will partic…

This study surveys 200 ICU doctors in Switzerland to understand how they use ultrasound to manage fluids and check for vein congestion. The goal is to learn what doctors know and how often they use these techniques. No treatments or procedures are tested—just a questionnaire.

This study checks if wearable devices can continuously and accurately measure body temperature in real-world settings. Twelve adults will wear a device and also swallow a small sensor to compare readings. The goal is to see if the data is complete and reliable, not to diagnose or…