New test could make diagnosis of thirst disorders easier for patients
NCT ID NCT07569861
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares a new diagnostic test using mannitol infusion to the standard hypertonic saline test for diagnosing the cause of polyuria-polydipsia syndrome (excessive urination and thirst). Researchers will enroll 144 adults to see if the mannitol test is as accurate and more comfortable for patients. The goal is to find a simpler way to diagnose conditions like arginine vasopressin deficiency and primary polydipsia.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Mannitol and hypertonic saline (diagnostic agents)
- What this could lead to
- If successful, this could provide a simpler, more comfortable diagnostic test for people with excessive thirst and urination, replacing the current standard test.
- What could go wrong
- This is a relatively small, early-phase diagnostic study. The mannitol test may not be as accurate as the standard test, and results may not apply to all patient groups.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University Hospital Basel
RECRUITINGBasel, 4031, Switzerland
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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