Hormone pill could unlock diagnosis of rare oxytocin deficiency in teens

NCT ID NCT07568509

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-phase trial is testing whether a single dose of a hormone pill can help diagnose oxytocin deficiency in young people with hypopituitarism. Researchers will give the pill to 20 participants and measure oxytocin-related substances in blood and saliva. The goal is to develop a simple provocation test for a condition that currently lacks a standard diagnostic method.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Norethindrone Acetate-Ethinyl Estradiol (a hormone pill)

What this could lead to

If successful, this could lead to a reliable diagnostic test for oxytocin deficiency, helping doctors identify and treat this condition in young people.

What could go wrong

This is a very early, small pilot study with only 20 participants. The test may not work as hoped, and results may not apply to everyone with hypopituitarism.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Diabetes Insipidus, Neurogenic hypopituitarism neurohypophyseal diabetes insipidus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Massachusetts General Hospital

    RECRUITING

    Boston, Massachusetts, 02114, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••