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Can a 'Love Hormone' spray boost sexual health in diabetes insipidus?

NCT ID NCT06808516

Recruiting now Symptom relief Sponsor: University Hospital, Basel, Switzerland Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase 2 trial tests whether oxytocin nasal spray can improve sexual well-being in people with central diabetes insipidus, a condition that also causes oxytocin deficiency. The study includes 42 participants (patients and healthy controls) and uses a double-blind, placebo-controlled crossover design. Participants will take the spray daily for a week or a single dose, and researchers will measure changes in sexual satisfaction and arousal.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
oxytocin nasal spray
What this could lead to
If it works, this could point toward a treatment for sexual well-being issues in people with central diabetes insipidus.
What could go wrong
This is a small early-phase trial with only 42 participants, so results may not apply broadly. The effect on sexual well-being may be modest or not statistically significant.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

central diabetes insipidus Diabetes Insipidus, Neurogenic neurohypophyseal diabetes insipidus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ARGININE VASOPRESSIN DEFICIENCY CENTRAL DIABETES INSIPIDUS OXYTOCIN DEFICIENCY

Contacts and locations

Locations

  • University Hospital Basel

    RECRUITING

    Basel, 4031, Switzerland

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