Can a common sedative stop ICU delirium in heavy drinkers?
NCT ID NCT07428681
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether giving lorazepam, a sedative, can prevent delirium in intensive care patients who are at high risk due to heavy alcohol use. Researchers will use a blood test (Anttila-Index) to identify these patients. The trial involves 260 adults admitted to the ICU, who will receive either lorazepam or a placebo every 6 hours for 3 days.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- lorazepam
- What this could lead to
- If it works, this could provide a simple way to prevent delirium in ICU patients with a history of heavy drinking, potentially reducing complications and hospital stays.
- What could go wrong
- This is a single-center trial with 260 participants, so results may not apply broadly. Lorazepam is a sedative and could cause side effects like drowsiness or dependence.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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Other studies related to the condition(s) this trial covers.
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