University Hospital, Antwerp

This study tests adding an immunotherapy drug (atezolizumab) and a personalized vaccine (WT1/DC) to standard chemotherapy for people with a type of mesothelioma. The goal is to see if this combination is safe and helps the immune system fight the cancer better. About 15 adults wi…

This study tests whether giving intensive care patients IV fluids with less salt (sodium and chloride) helps them recover faster. 640 adults expected to stay in the ICU for several days will be randomly assigned to receive either standard saltwater fluids or lower-salt alternativ…

This study tests a structured program to find and treat obstructive sleep apnea in people with atrial fibrillation (AFib). Participants use a home breathing monitor and a Fitbit smartwatch to track heart rhythm. If sleep apnea is found, they receive standard treatment like CPAP. …

This registry follows 225 adults with moderate to severe obstructive sleep apnea who cannot use standard CPAP machines. They receive an implanted device that stimulates a nerve to keep the airway open during sleep. The study measures how well the device reduces breathing pauses a…

This study tests whether adding a blood-filtering device called CytoSorb to standard hospital care helps people with acute-on-chronic liver failure. About 20 adults with severe jaundice and confusion will receive the device for 72 hours. Researchers will measure changes in biliru…

This study tests if a special activity score, called the Antwerp Activity Index (AAI), can help people who finished a hospital-based heart rehab program stay physically active. About 318 adults will wear a smartwatch for 4 months to track their heart rate and activity. Some will …

This study compares two types of corneal transplant surgery (DSAEK and DMEK) in 220 adults with corneal swelling or Fuchs' dystrophy. The goal is to see which surgery gives better vision and quality of life over 12 months. Participants will be randomly assigned to one surgery and…

This study is testing a new blood test (T-cell activation test) to see if it can reliably diagnose amoxicillin allergy. About 300 people with a suspected allergy will give blood samples and may have skin tests. The goal is to improve accuracy so people don't avoid amoxicillin unn…

This study looks at whether eccentric muscle training (lengthening muscles under load) can improve strength and exercise ability in people with heart failure and reduced pumping function. About 3 participants will try either eccentric training or standard rehab exercises. The goa…

This study looks at how a nerve stimulator for the tongue (hypoglossal nerve stimulation) changes the way the upper airway collapses during sleep in people with obstructive sleep apnea. Researchers will use a sleep endoscopy and a new non-invasive method to measure collapse befor…

This study is observing 400 children in intensive care who need a breathing tube. Researchers want to see if the amount of air leaking around the tube can predict stridor (noisy, difficult breathing) after the tube is removed. The goal is to better understand and potentially prev…

This study looks at how common muscle loss and weakness are in people with liver cirrhosis, and how malnutrition plays a role. Researchers will use ultrasound to measure muscle size and a grip test to check strength. The goal is to better understand the problem and its impact on …

This study looks at whether a simple saliva test can find people at high risk for lung cancer more accurately than asking about their smoking history. Researchers will collect saliva from about 1,000 adults aged 50-74 and check for DNA changes linked to smoking. The goal is to cr…

This study looks at how the mix of bacteria and viruses in the airways of children with long-lasting bacterial bronchitis affects their immune system and breathing health. Researchers will also see how the standard antibiotic treatment, azithromycin, changes these germs and immun…

This study aims to improve how doctors monitor Barrett's esophagus, a condition that can lead to esophageal cancer. Researchers will collect tissue samples using a brush during routine endoscopy, along with blood and biopsy samples, from 50 adults with Barrett's esophagus. They w…

This study is testing a new ultrasound device (Hepatoscope) to screen for liver scarring and fat buildup in 200 adults who are at risk for chronic liver disease. Participants will get the scan, and if it shows signs of scarring, they will be referred to a liver specialist. The go…

This study is testing a mobile app designed to help people with atrial fibrillation or heart failure manage their condition from home. Researchers want to see if the app is easy to use, keeps patients engaged over time, and whether patients are satisfied with it. The study involv…

This study is testing whether using a blood test (liquid biopsy) to monitor treatment response can help people with advanced colorectal cancer maintain a better quality of life. About 150 adults starting their first treatment for cancer that has spread will be randomly assigned t…

This study reviews medical records of 200 children with obstructive sleep apnea who had tonsil surgery. The goal is to see how often breathing problems happen after surgery, especially in children with conditions like obesity, Down syndrome, or neurological disorders. The finding…

This study tests whether patients with serious infections who are at risk for sepsis can be safely monitored at home using wearable devices and a smartphone app. About 120 adults will take part, and the goal is to see if this approach can reduce hospital visits while still catchi…

This study interviews 30 adults who are anxious about their upcoming elective surgery. The goal is to learn what specifically worries them, so doctors can better identify those at risk for long-term pain after surgery. This information will help create personalized care plans in …

This study follows 100 adults with rectal cancer to see how bowel function changes over two years after surgery. Participants may receive different treatments before surgery, and the goal is to identify which factors lead to better or worse bowel outcomes. The results could help …

This study aims to learn where the vaginal microbiome comes from and how it is passed between people. Researchers will recruit up to 500 women, their mothers, and close contacts in Belgium. Participants will provide swabs and stool samples, and some will give weekly samples for f…

This study looks at whether a daytime sleep test works as well as an overnight one to adjust the Inspire device for people with obstructive sleep apnea. About 110 adults who already have the Inspire implant will take part. The goal is to see if daytime testing can save time and r…