Tampere University Hospital

This study compares two common surgeries for uterine prolapse (when the womb drops down). About 426 women will be randomly assigned to have either a Manchester procedure or a vaginal hysterectomy. Researchers will track success rates, symptom relief, and quality of life for up to…

This study tests whether a semi-occlusive dressing (a special film changed weekly) works better than surgery for treating single fingertip amputations in adults. About 252 participants will be randomly assigned to either dressing or standard surgery. The main goal is to see which…

This study is testing whether people with rectal cancer who have a complete response to initial therapy can safely avoid surgery and instead be closely monitored. Researchers will track 200 participants to see how often the cancer stays away or comes back. The goal is to preserve…

This study is testing whether a urine test that looks for tumor DNA can find bladder and urinary tract cancers early in people with Lynch syndrome, a genetic condition that raises cancer risk. About 200 participants aged 50–75 will provide urine samples and be followed for one ye…

This study is testing whether a simple urine test that looks for tumor DNA can replace the standard invasive cystoscopy (a camera inserted into the bladder) for diagnosing bladder cancer. Researchers will enroll 3,000 people who have blood in their urine and are scheduled for a c…

This study looks at whether high-flow nasal therapy can help relieve severe breathlessness in people receiving palliative care. About 40 patients will try both the nasal therapy and a fan blowing air on their face for 30 minutes each. Researchers will ask how their breathing feel…

This study looks at whether two common treatments—an inhaled steroid (fluticasone) for dry cough and an antibiotic (amoxicillin-clavulanic acid) for wet cough—actually help children with a cough lasting more than four weeks. About 100 generally healthy children will be randomly a…

This study tests whether giving antibiotics through a small, portable pump over 24 hours is safe and cost-effective for children with serious bacterial infections. About 150 kids who are stable enough for home care will receive the pump instead of multiple daily hospital injectio…

This study compares an 8-week mindfulness-based stress reduction (MBSR) course to standard care for working-age adults (18–64) with back pain lasting over 12 weeks. Half of the 120 participants will take the course, and all will be followed for 2 years. The goal is to see if mind…

This study tests whether ultrasound-guided nerve blocks (TAP, RS, or both) can reduce pain and opioid use after open inguinal hernia surgery. 200 adults will be randomly assigned to receive one of the blocks or a placebo, alongside standard care. The goal is to see if these block…

This study looks at whether older adults (65+) with a displaced wrist fracture can be treated with just a cast, without first straightening the bone (closed reduction). The trial will compare pain and disability at 12 months between those who get a cast only and those who get the…

This study compares two ways to treat painful wrist ganglions (fluid-filled lumps). Half of the 220 adult participants will have surgery to remove the ganglion, while the other half will do exercises and use their hand normally. Researchers will measure pain, function, and satisf…

This study is collecting small intestine tissue samples from 300 adults to better understand and diagnose celiac disease and other small-bowel conditions. Researchers will use advanced techniques like AI image analysis and genetic profiling to create more reliable diagnostic tool…

This study is looking at 3,500 adults with celiac disease, dermatitis herpetiformis (a related skin condition), and their healthy friends or family. Researchers want to find genetic and biological markers that explain why the disease looks different in different people. No treatm…

This study looks at how modern, minimally invasive lung cancer surgery affects the heart's electrical signals. Researchers will monitor 100 adults before, during, and after surgery to see if temporary changes occur. The goal is to better understand the heart stress caused by the …