Could skipping surgery be safe for some rectal cancer patients?
NCT ID NCT06328361
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study is testing whether people with rectal cancer who have a complete response to initial therapy can safely avoid surgery and instead be closely monitored. Researchers will track 200 participants to see how often the cancer stays away or comes back. The goal is to preserve the rectum and avoid the side effects of surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
nonoperative surveillance (watch-and-wait monitoring with exams and scans)
What this could lead to
If successful, this approach could allow many rectal cancer patients to avoid major surgery and its side effects while still keeping the cancer under control.
What could go wrong
This is an early, single-arm study with no comparison group, so results may not apply broadly. There is a risk that the cancer may regrow, requiring delayed surgery.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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East Tallinn Central Hospital
RECRUITINGTallinn, Estonia
Contact Email: •••••@•••••
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Helsinki University Central Hospital
RECRUITINGHelsinki, 00290, Finland
Contact Email: •••••@•••••
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Jyväskylä Central Hospital
RECRUITINGJyväskylä, Finland
Contact Email: •••••@•••••
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Kuopio University Hospital
RECRUITINGKuopio, Finland
Contact Email: •••••@•••••
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North Estonia Medical Centre
RECRUITINGTallinn, Estonia
Contact Email: •••••@•••••
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Oulu University Hospital
RECRUITINGOulu, Finland
Contact Email: •••••@•••••
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Satakunta Central Hospital
RECRUITINGPori, Finland
Contact Email: •••••@•••••
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Seinajoki Central Hospital
RECRUITINGSeinäjoki, Finland
Contact Email: •••••@•••••
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Tampere University Hospital
RECRUITINGTampere, 33400, Finland
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Tartu University Hospital
RECRUITINGTartu, Estonia
Contact Email: •••••@•••••
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Turku University Hospital
RECRUITINGTurku, Finland
Contact Email: •••••@•••••
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Vaasa Central Hospital
NOT_YET_RECRUITINGVaasa, 65100, Finland
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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West Tallinn Central Hospital
RECRUITINGTallinn, Estonia
Contact Email: •••••@•••••